The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway.

Publié en juin 2011 PLoS biology

CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) β2, and prevents death-inducing signaling complex formation.

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Calcium store contents control the expression of TRPC1, TRPC3 and TRPV6 proteins in LNCaP prostate cancer cell line.

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Auteurs

Tauzin S
Chaigne-Delalande B
Selva E
Khadra N
Daburon S
Contin-Bordes C
Blanco P
Le Seyec J
Ducret T
Counillon L
Moreau JF
Hofman P
Legembre P