Clément BOUCHET

Teaching Researcher

Professional background

Since November 2024: LRU Teaching Researcher

Team 1 “Physiopathology of the pulmonary circulation”

Bordeaux Cardio-Thoracic Research Center, INSERM U1045

UFR des Sciences Pharmaceutiques, Collège Sciences de la Santé, Université de Bordeaux

 

November 2020 to May 2024: University thesis in pathophysiology

Team 1 “Pathophysiology of the pulmonary circulation”

Bordeaux Cardio-Thoracic Research Center, INSERM U1045

Project: Expression and role of nerve growth factor NGF in pulmonary hypertension

 

2018-2020: Master 1 (2 months) and 2 (6 months) internships

Team 1 “Physiopathology of the pulmonary circulation”

Bordeaux Cardio-Thoracic Research Center, INSERM U1045

Project: Role of NGF in pulmonary hypertension

Formations

 

  • November 2020-May 2024: PhD in pathophysiology

Bordeaux University

Training in animal experimentation: designer level, surgical training

MOOCs scientific integrity and research ethics

 

  • 2018-2020: Master’s degree in Cell Biology, Physiology and Pathology

Bordeaux University (with distinction, 1/18)

 

  • 2015-2018: Bachelor’s degree in life sciences: Biology and Life sciences

Bordeaux University (with merit, 49/456)

 

Funding

– Thesis funding

FRM Medical Research Foundation grant, Prix Jeanne-Philippe Béziat 2020

FRM Code: PBR202006012254

Funding for 3 years (2020-2023)

 

– End-of-thesis funding

End-of-thesis grant from the Groupe de Réflexion sur la Recherche Cardiovasculaire (GRRC)

Subsidiary of the Société Française de Cardiologie (SFC)

Funding for 6 months (2023-2024)

Publications 5

June 2025 iScience

Bronchial smooth muscle extracellular vesicles interfere with bronchial epithelium metabolism and function in asthma

Authors : Elisa Celle, Amine Chahin, Fabien Beaufils, Guillaume Cardouat, Edmée Eyraud, Clément Bouchet, Marilyne Campagnac, Olga Ousova, Hugues Begueret, Matthieu Thumerel, Rémi Dubois, Jean-William Dupuy, Thierry Leste-Lasserre, Sabrina Lacomme, Nina Lager-Lachaud, Floriant Bellvert, Roger Marthan, Pierre-Olivier Girodet, Patrick Berger, Thomas Trian, Pauline Esteves
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April 2025 American Journal of Respiratory Cell and Molecular Biology

CXCR4 Blockade Alleviates Pulmonary and Cardiac Outcomes in Early COPD

Authors : Isabelle Dupin, Pauline Henrot, Elise Maurat, Reshed Abohalaka, Sébastien Chaigne, Dounia El Hamrani, Edmée Eyraud, Renaud Prevel, Pauline Esteves, Marilyne Campagnac, Marielle Dubreuil, Guillaume Cardouat, Clément Bouchet, Olga Ousova, Jean-William Dupuy, Thomas Trian, Matthieu Thumerel, Hugues Begueret, Pierre-Olivier Girodet, Roger Marthan, Maeva Zysman, Véronique Freund-Michel, Patrick Berger
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May 2024 Biomedicine & Pharmacotherapy

NGF increases Connexin-43 expression and function in pulmonary arterial smooth muscle cells to induce pulmonary artery hyperreactivity

Authors : Guillaume Cardouat, Matthieu Douard, Clément Bouchet, Lukas Roubenne, Zuzana Kmecová, Pauline Esteves, Fabien Brette, Christophe Guignabert, Ly Tu, Marilyne Campagnac, Paul Robillard, Florence Coste, Frédéric Delcambre, Matthieu Thumerel, Hugues Begueret, Arnaud Maurac, Yaniss Belaroussi, Jan Klimas, Thomas Ducret, Jean-François Quignard, Pierre Vacher, Isabelle Baudrimont, Roger Marthan, Patrick Berger, Christelle Guibert, Véronique Freund-Michel
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April 2024 Revue des Maladies Respiratoires

Le facteur de croissance des nerfs (NGF) dans l’hypertension pulmonaire (HTP)

Authors : C. Bouchet, C. Guibert, V. Freund-Michel
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September 2022 Cells

Inflammation and Oxidative Stress Induce NGF Secretion by Pulmonary Arterial Cells through a TGF-β1-Dependent Mechanism

Authors : Clément Bouchet, Guillaume Cardouat, Matthieu Douard, Florence Coste, Paul Robillard, Frédéric Delcambre, Thomas Ducret, Jean-François Quignard, Pierre Vacher, Isabelle Baudrimont, Roger Marthan, Patrick Berger, Christelle Guibert, Véronique Freund-Michel
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