August 2026
PLOS One
Role of connexin 43 in hyperoxia-induced bronchopulmonary dysplasia and associated pulmonary hypertension
Authors : Claire-Marie Pilard, Christopher Torrens, Laure Gassiat, Guillaume Cardouat, Isabel Gauthereau, Paul Robillard, Eric Dumas-de-la-Roque, Fanny Sauvestre, Fanny Pelluard, Sophie Berenguer, Melie Sarreau, Loïc Sentilhes, Fréderic Coatleven, Marie Vincienne, Roger Marthan, Patrick Berger, Véronique Freund-Michel, Christelle Guibert
June 2026
NMR in biomedicine
Preclinical Quantitative In Vivo MRI Assessment of Exogenous Surfactant Pulmonary Distribution After Clinically Relevant Intratracheal Delivery.
Authors : Marfouk O, Gérard R, Kaouane G, Leclerc L, Pinaud N, Fayon M, Périnel-Ragey S, Pourchez J, De La Roque ED, Crémillieux Y
October 2025
Pediatric research
Closing the gap before using L-lactate to guide newborn care.
Authors : Roumes H, Ibrahim IO, Beauvieux MC, Perrot C, Brissaud O, Cramaregeas S, Dumas-de-la-Roque E, Pellerin L, Chateil JF, Tandonnet O, Bouzier-Sore AK
June 2025
NMR in biomedicine
MR Imaging of Pulmonary Surfactant Distribution in a Preclinical Neonatal Lung Model.
Authors : Marfouk O, Kaouane G, Leclerc L, Munsch F, Zhang B, Pinaud N, Gérard R, Fayon M, Périnel-Ragey S, de la Roque ED, Pourchez J, Crémillieux Y
May 2025
Scientific reports
Characterization of atomization and delivery efficiency of exogenous surfactant in preterm infant lungs using an ex vivo respiratory model.
Authors : Kaouane G, Berret JF, Cremillieux Y, Pinaud N, Munsch F, Zhang B, Fayon M, Gérard R, De La Roque ED, Perinel-Ragey S, Leclerc L, Pourchez J
March 2025
Biomedicine & Pharmacotherapy
Celastrol has beneficial effects on pulmonary hypertension associated with bronchopulmonary dysplasia: Preclinical study outcomes
Authors : Claire-Marie Pilard, Guillaume Cardouat, Isabel Gauthereau, Laure Gassiat, Mathilde Dubois, Paul Robillard, Fanny Sauvestre, Fanny Pelluard, Sophie Berenguer, Melie Sarreau, Stéphane Claverol, Caroline Tokarski, Loïc Sentilhes, Frederic Coatleven, Marie Vincienne, Roger Marthan, Eric Dumas-de-la-roque, Patrick Berger, Mark K. Friedberg, Laurent Renesme, Véronique Freund-Michel, Christelle Guibert
March 2025
Pediatric research
Positive impact of sodium L-lactate supplementation on blood acid-base status in preterm newborns.
Authors : Omar Ibrahim I, Perrot C, Roumes H, Beauvieux MC, Brissaud O, Cramaregeas S, Dumas-de-la-Roque E, Pellerin L, Chateil JF, Tandonnet O, Bouzier-Sore AK
July 2020
Pediatric pulmonology
Nasal high-frequency percussive ventilation vs nasal continuous positive airway pressure in newborn infants respiratory distress: A cross over clinical trial.
Authors : Renesme L, Dumas de la Roque E, Germain C, Chevrier A, Rebola M, Cramaregeas S, Benard A, Elleau C, Tandonnet O
March 2020
The European respiratory journal
Connexin-43 is a promising target for pulmonary hypertension due to hypoxaemic lung disease.
Authors :
February 2020
Nasal high-frequency percussive ventilation versus nasal continuous positive airway pressure in term and preterm neonates exhibiting respiratory distress: a randomized controlled trial (TONIPEP; NCT 02030691)
Authors : Laurent R, Eric DdlR, Christine G, Agnès C, Muriel R, Sophie C, Antoine B, Christophe E, Olivier T
June 2018
Archives of cardiovascular diseases
Toward the integration of global longitudinal strain analysis in the assessment of neonatal aortic coarctation? A preliminary study.
Authors : Séguéla PE, Thomas-Chabaneix J, Jalal Z, Roubertie F, Faydi L, Mouton JB, Dumas-de-la-Roque E, Tandonnet O, Pillois X, Thambo JB, Iriart X
February 2017
PloS one
Altered vasoreactivity in neonatal rats with pulmonary hypertension associated with bronchopulmonary dysplasia: Implication of both eNOS phosphorylation and calcium signaling.
Authors : Dumas de la Roque E, Smeralda G, Quignard JF, Freund-Michel V, Courtois A, Marthan R, Muller B, Guibert C, Dubois M
May 2013
Pediatric research
Beneficial effect of dehydroepiandrosterone on pulmonary hypertension in a rodent model of pulmonary hypertension in infants.
Authors : Dumas de la Roque E, Quignard JF, Ducret T, Dahan D, Courtois A, Begueret H, Marthan R, Savineau JP
December 2012
Biochemical pharmacology
Role of DHEA in cardiovascular diseases.
Authors : Savineau JP, Marthan R, Dumas de la Roque E
May 2012
Pediatric pulmonology
Effect of high-frequency oscillation and percussion versus conventional ventilation in a piglet model of meconium aspiration.
Authors : Renesme L, Elleau C, Nolent P, Fayon M, Marthan R, Dumas De La Roque E
April 2012
The European respiratory journal
Dehydroepiandrosterone reverses chronic hypoxia/reoxygenation-induced right ventricular dysfunction in rats.
Authors : Dumas de La Roque E, Bellance N, Rossignol R, Begueret H, Billaud M, dos Santos P, Ducret T, Marthan R, Dahan D, Ramos-Barbón D, Amor-Carro Ó, Fayon M
January 2012
Annales d'endocrinologie
Dehydroepiandrosterone (DHEA) improves pulmonary hypertension in chronic obstructive pulmonary disease (COPD): a pilot study.
Authors : Dumas de La Roque E, Savineau JP, Metivier AC, Billes MA, Kraemer JP, Doutreleau S, Jougon J, Marthan R, Moore N, Fayon M, Baulieu EÉ, Dromer C
March 2011
Circulation
Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension.
Authors : Paulin R, Courboulin A, Meloche J, Mainguy V, Dumas de la Roque E, Saksouk N, Côté J, Provencher S, Sussman MA, Bonnet S
October 2010
NMR in biomedicine
Effect of chronic hypoxia on pulmonary artery blood velocity in rats as assessed by electrocardiography-triggered three-dimensional time-resolved MR angiography.
Authors : de La Roque ED, Thiaudière E, Ducret T, Marthan R, Franconi JM, Guibert C, Parzy E
October 2010
Pediatric pulmonology
Nasal high frequency percussive ventilation versus nasal continuous positive airway pressure in transient tachypnea of the newborn: a pilot randomized controlled trial (NCT00556738).
Authors : Dumas De La Roque E, Bertrand C, Tandonnet O, Rebola M, Roquand E, Renesme L, Elleau C
March 2010
Pharmacology & therapeutics
Dehydroepiandrosterone: A new treatment for vascular remodeling diseases including pulmonary arterial hypertension.
Authors : Dumas de la Roque E, Savineau JP, Bonnet S
August 2009
Pediatrics
Propranolol for severe infantile hemangiomas: follow-up report.
Authors : Sans V, de la Roque ED, Berge J, Grenier N, Boralevi F, Mazereeuw-Hautier J, Lipsker D, Dupuis E, Ezzedine K, Vergnes P, Taïeb A, Léauté-Labrèze C
June 2008
The New England journal of medicine
Propranolol for severe hemangiomas of infancy.
Authors : Léauté-Labrèze C, Dumas de la Roque E, Hubiche T, Boralevi F, Thambo JB, Taïeb A
November 2006
Neonatology
Efficacy and tolerance of high-dose inhaled ipratropium bromide vs. terbutaline in intubated premature human neonates.
Authors : Fayon M, Tayara N, Germain C, Choukroun ML, De La Roque ED, Chêne G, Breilh D, Marthan R, Demarquez JL
December 2004
Journal of applied physiology (Bethesda, Md. : 1985)
Increased relaxation of immature airways to beta2-adrenoceptor agonists is related to attenuated expression of postjunctional smooth muscle muscarinic M2 receptors.
Authors : Fayon M, Dumas De La Roque E, Berger P, Begueret H, Ousova O, Molimard M, Marthan R
September 2004
American journal of physiology. Heart and circulatory physiology
Chronic hypoxia induces nonreversible right ventricle dysfunction and dysplasia in rats.
Authors : Bonnet P, Bonnet S, Boissière J, Le Net JL, Gautier M, Dumas de la Roque E, Eder V
July 2003
Proceedings of the National Academy of Sciences of the United States of America
Dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary hypertension.
Authors : Bonnet S, Dumas-de-La-Roque E, Bégueret H, Marthan R, Fayon M, Dos Santos P, Savineau JP, Baulieu EE
July 2001
Critical care (London, England)
Overdistension in ventilated children.
Authors : Nève V, Leclerc F, de la Roque ED, Leteurtre S, Riou Y