Members

Marilyne CAMPAGNAC

Assistant Engineer in animal biology, teams 1 and 2

Email : [email protected]
ORCID : 0009-0002-8416-838X

Professional background

Since 2025 : Research Engineer in Animal Biology – CRCTB – INSERM U1045 – University of Bordeaux
2013-2025 : Senior Research and Training Technician, Animal Experimentation – CRCTB (Teams 1 and 2) – INSERM U1045 – University of Bordeaux – Pessac
2009-2011 : Animal Care Volunteer at the “Discover and Help Nature” Refuge – Djibouti
2008-2009 : Senior Laboratory Technician, Therapeutic Molecule Testing on Isolated Hearts – INSERM U1034 – Pessac
2007-2008 : Assistant, Maintenance and Monitoring of Transgenic Lines – Institute of Pharmacology and Structural Biology – Toulouse
2007 : Animal Technician, creation of transgenic mice – Rangueil University Hospital – Toulouse
2006 : Laboratory Technician, gene expression study on GMOs – Syngenta – St Sauveur
2006 : Professional Bachelor’s Degree in Animal Production (work-study program – University of Grenoble), specializing in physiology and pathophysiology with a focus on pharmacology, Level 2 certification in animal experimentation.

Publications 20

June 2025 iScience

Bronchial smooth muscle extracellular vesicles interfere with bronchial epithelium metabolism and function in asthma

Authors : Elisa Celle, Amine Chahin, Fabien Beaufils, Guillaume Cardouat, Edmée Eyraud, Clément Bouchet, Marilyne Campagnac, Olga Ousova, Hugues Begueret, Matthieu Thumerel, Rémi Dubois, Jean-William Dupuy, Thierry Leste-Lasserre, Sabrina Lacomme, Nina Lager-Lachaud, Floriant Bellvert, Roger Marthan, Pierre-Olivier Girodet, Patrick Berger, Thomas Trian, Pauline Esteves
Read more
April 2025 American Journal of Respiratory Cell and Molecular Biology

CXCR4 Blockade Alleviates Pulmonary and Cardiac Outcomes in Early COPD

Authors : Isabelle Dupin, Pauline Henrot, Elise Maurat, Reshed Abohalaka, Sébastien Chaigne, Dounia El Hamrani, Edmée Eyraud, Renaud Prevel, Pauline Esteves, Marilyne Campagnac, Marielle Dubreuil, Guillaume Cardouat, Clément Bouchet, Olga Ousova, Jean-William Dupuy, Thomas Trian, Matthieu Thumerel, Hugues Begueret, Pierre-Olivier Girodet, Roger Marthan, Maeva Zysman, Véronique Freund-Michel, Patrick Berger
Read more
April 2025 American journal of respiratory cell and molecular biology

CXCR4 Blockade Alleviates Pulmonary and Cardiac Outcomes in Early COPD.

Authors : Dupin I, Henrot P, Maurat E, Abohalaka R, Chaigne S, El Hamrani D, Eyraud E, Prevel R, Esteves P, Campagnac M, Dubreuil M, Cardouat G, Bouchet C, Ousova O, Dupuy JW, Trian T, Thumerel M, Begueret H, Girodet PO, Marthan R, Zysman M, Freund-Michel V, Berger P
Read more
May 2024 Biomedicine & Pharmacotherapy

NGF increases Connexin-43 expression and function in pulmonary arterial smooth muscle cells to induce pulmonary artery hyperreactivity

Authors : Guillaume Cardouat, Matthieu Douard, Clément Bouchet, Lukas Roubenne, Zuzana Kmecová, Pauline Esteves, Fabien Brette, Christophe Guignabert, Ly Tu, Marilyne Campagnac, Paul Robillard, Florence Coste, Frédéric Delcambre, Matthieu Thumerel, Hugues Begueret, Arnaud Maurac, Yaniss Belaroussi, Jan Klimas, Thomas Ducret, Jean-François Quignard, Pierre Vacher, Isabelle Baudrimont, Roger Marthan, Patrick Berger, Christelle Guibert, Véronique Freund-Michel
Read more
January 2024 Respiratory Research

Pulmonary adaptation to repeated poly(I:C) exposure is impaired in asthmatic mice: an observational study

Authors : Allard, B., Ousova, O., Savitskaya, Z., Levardon, H., Maurat, E., Campagnac, M., Trian, T., Berger, P.
Read more
September 2023 Molecular pathology and functional genomics

Blocking CXCR4 improves pulmonary and cardiac outcomes in a mouse model of early COPD

Authors : Isabelle Dupin, Pauline Henrot, Elise Maurat, Reshed Abohalaka, Sébastien Chaigne, Dounia El Hamrani, Edmée Eyraud, Renaud Prevel, Pauline Estèves, Marilyne Campagnac, Marielle Dubreuil, Guillaume Cardouat, Clément Bouchet, Olga Ousova, Jean-William Dupuy, Thomas Trian, Matthieu Thumerel, Hugues Bégueret, Pierre-Olivier Girodet, Roger Marthan, Maéva Zysman, Véronique Freund-Michel, Patrick Berger
Read more
September 2023 Molecular pathology and functional genomics

Involvement of the CXCR4/CXCL12 axis in skeletal muscle wasting in a murine model of Chronic Obstructive Pulmonary Disease (COPD)

Authors : Pauline Henrot, Pierre Schilfarth, Marilyne Campagnac, Elise Maurat, Pauline Estèves, Jean-William Dupuy, Reshed Abohalaka, Olivier Chassande, Maéva Zysman, Patrick Berger, Isabelle Dupin
Read more
July 2023 British Journal of Pharmacology

OP2113, a new drug for chronic hypoxia‐induced pulmonary hypertension treatment in rat

Authors : Lukas Roubenne, Margaux Laisné, David Benoist, Marilyne Campagnac, Bénédicte Prunet, Philippe Pasdois, Guillaume Cardouat, Thomas Ducret, Jean‐François Quignard, Pierre Vacher, Isabelle Baudrimont, Roger Marthan, Patrick Berger, Bruno Le Grand, Véronique Freund‐Michel, Christelle Guibert
Read more
March 2023 01.02 - Rehabilitation and chronic care

Involvement of the CXCL12/CXCR4 axis in skeletal muscle wasting in a murine model of early Chronic Obstructive Pulmonary Disease (COPD)

Authors : P Henrot, P Schilfarth, M Campagnac, E Maurat, P Estèves, J Dupuy, R Abohalaka, M Zysman, P Berger, I Dupin
Read more
February 2023 Revue des Maladies Respiratoires

Involvement of the CXCR4/CXCL12 axis in skeletal muscle wasting in a murine model of chronic obstructive pulmonary disease (COPD)

Authors : P. Schilfarth, M. Campagnac, E. Maurat, R. Abohalaka, M. Zysman, P. Berger, I. Dupin, P. Henrot
Read more
February 2023 Revue des Maladies Respiratoires

Targeting CXCR4 as a therapeutic strategy to improve outcomes in a mouse model of early chronic obstructive pulmonary disease (COPD)

Authors : I. Dupin, P. Henrot, R. Abohalaka, E. Maurat, E. Eyraud, P. Esteves, M. Zysman, M. Campagnac, M. Dubreuil, G. Cardouat, C. Bouchet, O. Ousova, T. Trian, V. Freund-Michel, P. Berger
Read more
March 2022 Airway pharmacology and treatment

Targeting CXCR4 as a therapeutic strategy to improve outcomes in a mouse model of early chronic obstructive pulmonary disease (COPD)

Authors : Isabelle Dupin, Pauline Henrot, Elise Maurat, Edmée Eyraud, Pauline Esteves, Maeva Zysman, Marilyne Campagnac, Marielle Dubreuil, Guillaume Cardouat, Clément Bouchet, Olga Ousova, Thomas Trian, Véronique Freund-Michel, Patrick Berger
Read more
February 2022 Revue des Maladies Respiratoires

Beneficial effects of a preventive treatment with anethole trithione on pulmonary hypertension

Authors : L. Roubenne, M. Laisné, M. Campagnac, R. Marthan, B. Le Grand, C. Guibert
Read more
January 2020 European Respiratory Journal

Connexin-43 is a promising target for pulmonary hypertension due to hypoxaemic lung disease

Authors : Bouvard, C., Genet, N., Phan, C., Rode, B., Thuillet, R., Tu, L., Robillard, P., Campagnac, M., Soleti, R., de la Roque, E.D., Delcambre, F., Cronier, L., Parpaite, T., Maurat, E., Berger, P., Savineau, J.-P., Marthan, R., Guignabert, C., Freund-Michel, V., Guibert, C.
Read more
January 2020 American Journal of Physiology-Lung Cellular and Molecular Physiology

TRPV4 channel mediates adventitial fibroblast activation and adventitial remodeling in pulmonary hypertension

Authors : Laure-Anne Cussac, Guillaume Cardouat, Nichiren Tiruchellvam Pillai, Marilyne Campagnac, Paul Robillard, Anaïs Montillaud, Christelle Guibert, Philippe Gailly, Roger Marthan, Jean-François Quignard, Jean-Pierre Savineau, Thomas Ducret
Read more
December 2019 Respiratory Research

Determination of reliable lung function parameters in intubated mice

Authors : Eline Bonnardel, Renaud Prevel, Marilyne Campagnac, Marielle Dubreuil, Roger Marthan, Patrick Berger, Isabelle Dupin
Read more
June 2019 American Journal of Respiratory Cell and Molecular Biology

Stretch-activated Piezo1 Channel in Endothelial Cells Relaxes Mouse Intrapulmonary Arteries

Authors : Audrey Lhomme, Guillaume Gilbert, Thomas Pele, Juliette Deweirdt, Daniel Henrion, Isabelle Baudrimont, Marilyne Campagnac, Roger Marthan, Christelle Guibert, Thomas Ducret, Jean-Pierre Savineau, Jean-François Quignard
Read more
March 2019 Monitoring Airway Disease

Targeting CXCR4 as a therapeutic strategy to improve outcomes in a mouse model of early chronic obstructive pulmonary disease (COPD)

Authors : Isabelle Dupin, Marielle Dubreuil, Véronique Freund-Michel, Elise Maurat, Marilyne Campagnac, Olga Ousova, Thomas Trian, Pierre-Olivier Girodet, Patrick Berger
Read more
April 2018 Archives of Cardiovascular Diseases Supplements

Role of connexin 43 in pulmonary hypertension in mice

Authors : C. Bouvard, N. Genet, P. Robillard, M. Campagnac, T. Parpaite, R. Marthan, J.P. Savineau, C. Guibert
Read more
April 2011 Cardiovascular Research

GSK-3β at the crossroads in the signalling of heart preconditioning: implication of mTOR and Wnt pathways

Authors : François Vigneron, Pierre Dos Santos, Sandrine Lemoine, Maryline Bonnet, Liliane Tariosse, Thierry Couffinhal, Cécile Duplaà, Béatrice Jaspard-Vinassa
Read more

Team

Team 2

Bronchial remodeling

The study of the mechanisms and treatments of bronchial remodeling in asthma and chronic bronchitis is at the heart of this team's work. It has recognized expertise in epithelium-muscle interactions, functional imaging and clinical research.

Leadership : Patrick BERGER