Matthieu DOUARD

Research Engineer

Professional background

Research Ingeneer
IHU LIRYC – INSERM U1045 l Dec 2024 – Today
• Project : « Identification of electrical substrates responsible of arrhythmic events from the right ventricle » (Supervisor: Dr David Benoist)
• Core Facility Manager – Electrophysiology and Microscopy

Post-Doctorat
INSERM U1045, TEAM 1 (Bordeaux) l Dec 2022 – Mar 2024
• Project : «Role of CD95 receptor in breast cancer tumoregenesis » (Supervisor: Dr Pierre Vacher)
• National collaboration (UMR CNRS 7276)

Doctorate
IHU LIRYC – INSERM U1045(Bordeaux) l Mar 2018 – Mar 2022
• Thesis: «Role of metabolism on cardiac excitation-contraction coupling: multi-species and multi-regions approaches» (Supervisor: Dr Brette Fabien)
• International collaboration (Leeds University, Pr Ed White)
• Supervision of interns

Master 2nd year internship
INSERM U1045, Pr Marthan R. lab (Bordeaux) l Jan – Jun 2017
• «Interaction between nerve growth factor (NGF) and GAP junctions in pulmonary hypertension» (Supervisor: Dr Freund-Michel Veronique)

Master 1st year internship
INSERM U1045, Pr Marthan R. lab (Bordeaux) l Apr – May 2016
• «Mechanisms of increased expression of nerve growth factor (NGF) in pulmonary hypertension» (Supervisor: Dr Freund-Michel Veronique)

Licence 3rd year internship
IRSET/INSERM UMR 1085, Dr Jegou B. lab (Rennes) l Apr – May 2015
• «Study of human primary macrophage infection by Pseudomonas aeruginosa » (Supervisor: Dr Dimanche-Boitrel MT)

Publications 6

January 2023 Jacc Clinical Electrophysiology

Functional Epicardial Conduction Disturbances Due to a SCN5A Variant Associated With Brugada Syndrome

Authors : Renard, E., Walton, R.D., Benoist, D., Brette, F., Bru-Mercier, G., Chaigne, S., Charron, S., Constantin, M., Douard, M., Dubes, V., Guillot, B., Hof, T., Magat, J., Martinez, M.E., Michel, C., Pallares-Lupon, N., Pasdois, P., Récalde, A., Vaillant, F., Sacher, F., Labrousse, L., Rogier, J., Kyndt, F., Baudic, M., Schott, J.-J., Barc, J., Probst, V., Sarlandie, M., Marionneau, C., Ashton, J.L., Hocini, M., Haïssaguerre, M., Bernus, O.
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January 2023 International Journal of Molecular Sciences

Regional Differences in Ca2+ Signaling and Transverse-Tubules across Left Atrium from Adult Sheep

Authors : Cros, C., Douard, M., Chaigne, S., Pasqualin, C., Bru-Mercier, G., Recalde, A., Pascarel-Auclerc, C., Hof, T., Haïssaguerre, M., Hocini, M., Jaïs, P., Bernus, O., Brette, F.
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September 2022 Cells

Inflammation and Oxidative Stress Induce NGF Secretion by Pulmonary Arterial Cells through a TGF-β1-Dependent Mechanism

Authors : Clément Bouchet, Guillaume Cardouat, Matthieu Douard, Florence Coste, Paul Robillard, Frédéric Delcambre, Thomas Ducret, Jean-François Quignard, Pierre Vacher, Isabelle Baudrimont, Roger Marthan, Patrick Berger, Christelle Guibert, Véronique Freund-Michel
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March 2022

Rôle du métabolisme dans la régulation du couplage excitation contraction cardiaque : approches multi-espèces et multi-régions.

Authors :
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July 2021 The Journal of Physiology

New insights into heart failure during this challenging time

Authors : Matthieu Douard
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January 2021 Cardiovascular Research

Transverse tubules strike back: may the junctophilin-2 be with you

Authors : Matthieu Douard, Fabien Brette
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