Olivier VILLEMAIN

Cardiologist

Professional background

Olivier Villemain did his medical training and undertook specialist training in paediatric cardiology in Paris, France. He graduated from medical school at Paris Descartes University in 2014.
Afterwards, he became Assistant Professor in Paediatric Cardiology at Necker Enfants Malades Hospital in Paris for two years. In addition to his medical training, he studied cardiovascular physiology (M.Sc., Paris Descartes University, 2014) and acoustic physics. Between 2014 and 2017, he worked at the Langevin Institute in Paris, a laboratory specialized in acoustic physics. This resulted in a PhD thesis on the new applications of ultrasound in cardiology in 2017. He worked full-time again in this laboratory, between November 2018 and July 2019, as a collaborator.
In July 2019, he was appointed as a clinician investigator and staff cardiologist at The Hospital for Sick Children (SickKids). He founded and led the Villemain Lab, the first laboratory in the world dedicated to the development and application of ultrafast ultrasound imaging in pediatrics. In just four years, his team published over 30 international publications on this topic.
In August 2023, Olivier Villemain returned to France to work at the Bordeaux University Hospital and the IHU Liryc, where he leads the Ultrafast Imaging team. In July 2025, he was awarded an ERC Starting Grant (5D-ULTRAFAST-HCM).

Funding

Research funding obtained (between 2018 and 2025): a total of €3,350,000, including an ERC Starting Grant (€1,500,000; 2025–2030) and a CIHR Operating Grant of $485,000 CAD (2022–2027, #202203PJT-183888). A total of 20 grants and 5 awards obtained as Principal Investigator.

Patents

Methods and Apparatus for Treating Valvular Disease. Granted. Patent #: 15/557455. United States. Messas E, Pernot M, Tanter M, and Villemain O;
Systems and Methods for Assessing Myocardial Work. Provisional. Patent #: P4920US00. Villemain O, Baranger J, Venet M, and Mertens L.

Publications 30

September 2020 Cardiology in the young

Antenatal occlusion of a ductal arteriosus aneurysm: a potential postnatal surgical emergency. Case report and literature review.

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August 2020 IEEE transactions on medical imaging

4D ultrafast ultrasound imaging of naturally occurring shear waves in the human heart.

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August 2020 Journal of investigative medicine : the official publication of the American Federation for Clinical Research

Saving the endangered physician-scientists: reintroducing them to an environment of administrative support.

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June 2020 Physics in medicine and biology

Quantitative imaging of coronary flows using 3D ultrafast Doppler coronary angiography.

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January 2020 Journal of hypertension

Changes in segmental pulse wave velocity of the thoracic aorta with age and left ventricular remodelling. An MRI 4D flow study.

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November 2019 JACC. Cardiovascular imaging

Ultrafast Ultrasound Imaging in Pediatric and Adult Cardiology: Techniques, Applications, and Perspectives.

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September 2019 Interactive cardiovascular and thoracic surgery

Risk factors of mortality and recoarctation after coarctation repair in infancy.

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May 2019 Cardiology in the young

Cardiac catheterisation in infants weighing less than 2500 grams.

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April 2019 Physics in medicine and biology

4D simultaneous tissue and blood flow Doppler imaging: revisiting cardiac Doppler index with single heart beat 4D ultrafast echocardiography.

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March 2019 Jacc. Cardiovascular Imaging

In the Heart of Stiffness: Are Natural Heart Vibrations Reliable Enough to Assess Myocardial Stiffness, The New Holy Grail in Echocardiography?

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September 2018 Journal of thoracic disease

Role of animal models for percutaneous atrial septal defect closure.

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July 2018 Cardiology in the young

Radiation exposure in transcatheter patent ductus arteriosus closure: time to tune? -CORRIGENDUM.

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May 2018 The Journal of Thoracic and Cardiovascular Surgery

What matters more in testing bacterial adhesion: Flow conditions or choice of bacterial strain?

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March 2018 JACC. Cardiovascular imaging

Myocardial Stiffness Evaluation Using Noninvasive Shear Wave Imaging in Healthy and Hypertrophic Cardiomyopathic Adults.

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March 2018 Archives of cardiovascular diseases

French national survey on infective endocarditis and the Melody™ valve in percutaneous pulmonary valve implantation.

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January 2018 Cardiology in the young

Radiation exposure in transcatheter patent ductus arteriosus closure: time to tune?

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January 2018 Jacc. Cardiovascular Imaging

Stone Liver, Heart in Danger: Could the Liver Stiffness Assessment Improve the Management of Patients With Heart Failure?

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December 2017 Archives of cardiovascular diseases

Percutaneous coronary artery interventions in the paediatric population: Periprocedural and late outcome.

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November 2017 Jacc. Cardiovascular Imaging

Myocardial Stiffness Assessment Using Shear Wave Imaging in Pediatric Hypertrophic Cardiomyopathy.

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October 2017 Archives of cardiovascular diseases

Reduction of radiation exposure in transcatheter atrial septal defect closure: How low must we go?

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August 2017 JACC. Cardiovascular imaging

Noninvasive Imaging of the Coronary Vasculature Using Ultrafast Ultrasound.

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August 2017 JACC. Basic to translational science

Pulsed Cavitational Ultrasound Softening: a new non-invasive therapeutic approach of calcified bioprosthetic valve stenosis.

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April 2017 Jacc. Cardiovascular Imaging

Toward Noninvasive Assessment of CVP Variations Using Real-Time and Quantitative Liver Stiffness Estimation.

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April 2017 Scientific reports

Imaging the dynamics of cardiac fiber orientation in vivo using 3D Ultrasound Backscatter Tensor Imaging.

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August 2016 European heart journal cardiovascular Imaging

Pulsed cavitational ultrasound for non-invasive chordal cutting guided by real-time 3D echocardiography.

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May 2016 The Journal of Thoracic and Cardiovascular Surgery

Impact of anatomic characteristics and initial biventricular surgical strategy on outcomes in various forms of double-outlet right ventricle.

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May 2016 Seminars in thoracic and cardiovascular surgery

Double-Outlet Right Ventricle With Noncommitted Ventricular Septal Defect and 2 Adequate Ventricles: Is Anatomical Repair Advantageous?

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February 2016 Seminars in thoracic and cardiovascular surgery

Double Outlet Right Ventricle with Noncommitted Ventricular Septal Defect and Two Adequate Ventricles: is Anatomical Repair Advantageous?

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February 2016 IEEE transactions on ultrasonics, ferroelectrics, and frequency control

Ultrafast Harmonic Coherent Compound (UHCC) Imaging for High Frame Rate Echocardiography and Shear-Wave Elastography.

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July 2015 International journal of cardiology

Selective propensity of bovine jugular vein material to bacterial adhesions: An in-vitro study.

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