Roger MARTHAN

University Professor–Hospital Practitioner

Professional background

Since 1993 : Professor of Physiology – Hospital Praticioner
1998-2010 : Director of Inserm – team (EMI n° 9937) renewed (E 356) in 2003 and in 2006 as an Inserm Unit U 885
2006-2010 : Director of Inserm Federate Institute of Research (IFR) n° 4 “Heart-Blood-Lung”
2006-2016 : Director of Doctoral School Biological and Health Sciences of the University of Bordeaux
2008-2013 : President of Biomedical Research Comitee of Bordeaux Teaching Hospital (Bordeaux CHU)
2010-2023 : Research Vice President of Bordeaux CHU
2011-2021 : Director of Inserm Bordeaux Cardio-Thoracic Research Centre (CRCTB)
2016-2025 : Director of the Graduate Research School of the University of Bordeaux

Funding

Inserm
Conseil Régional d’Aquitaine
National Research Agency (ANR)
Medical Research Foundation (FRM)
Ministry of Environnement

Publications 268

April 2025 American Journal of Respiratory Cell and Molecular Biology

CXCR4 Blockade Alleviates Pulmonary and Cardiac Outcomes in Early COPD

Authors : Isabelle Dupin, Pauline Henrot, Elise Maurat, Reshed Abohalaka, Sébastien Chaigne, Dounia El Hamrani, Edmée Eyraud, Renaud Prevel, Pauline Esteves, Marilyne Campagnac, Marielle Dubreuil, Guillaume Cardouat, Clément Bouchet, Olga Ousova, Jean-William Dupuy, Thomas Trian, Matthieu Thumerel, Hugues Begueret, Pierre-Olivier Girodet, Roger Marthan, Maeva Zysman, Véronique Freund-Michel, Patrick Berger
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April 2025 iScience

Bronchial smooth muscle extracellular vesicles interfere with bronchial epithelium metabolism and function in asthma

Authors : Celle E, Chahin A, Beaufils F, Cardouat G, Eyraud E, Bouchet C, Campagnac M, Ousova O, Begueret H, Thumerel M, Dubois R, Dupuy J, Leste-Lasserre T, Esteves P
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March 2025 Biomedicine & Pharmacotherapy

Celastrol has beneficial effects on pulmonary hypertension associated with bronchopulmonary dysplasia: Preclinical study outcomes

Authors : Claire-Marie Pilard, Guillaume Cardouat, Isabel Gauthereau, Laure Gassiat, Mathilde Dubois, Paul Robillard, Fanny Sauvestre, Fanny Pelluard, Sophie Berenguer, Melie Sarreau, Stéphane Claverol, Caroline Tokarski, Loïc Sentilhes, Frederic Coatleven, Marie Vincienne, Roger Marthan, Eric Dumas-de-la-roque, Patrick Berger, Mark K. Friedberg, Laurent Renesme, Véronique Freund-Michel, Christelle Guibert
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April 2024 Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

NGF increases Connexin-43 expression and function in pulmonary arterial smooth muscle cells to induce pulmonary artery hyperreactivity.

Authors : Cardouat G, Douard M, Bouchet C, Roubenne L, Kmecová Z, Esteves P, Brette F, Guignabert C, Tu L, Campagnac M, Robillard P, Coste F, Delcambre F, Thumerel M, Begueret H, Maurac A, Belaroussi Y, Klimas J, Ducret T, Quignard JF, Vacher P, Baudrimont I, Marthan R, Berger P, Guibert C, Freund-Michel V
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July 2023 British journal of pharmacology

OP2113, a new drug for chronic hypoxia-induced pulmonary hypertension treatment in rat.

Authors : Roubenne L, Laisné M, Benoist D, Campagnac M, Prunet B, Pasdois P, Cardouat G, Ducret T, Quignard JF, Vacher P, Baudrimont I, Marthan R, Berger P, Guibert C
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November 2022 European journal of nuclear medicine and molecular imaging

On the factors affecting the liver SUV in [18F]FDG PET/CT imaging.

Authors : Laffon E, de Clermont H, Marthan R
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October 2022 Cancer biotherapy & radiopharmaceuticals

64Cu-/177Lu-Cetuximab Theranostic Pair: May the Single 64Cu-Cetuximab Diagnostic Scan Be Acquired at Any Time After Injection?

Authors : Laffon E, Marthan R
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September 2022 Cells

Inflammation and Oxidative Stress Induce NGF Secretion by Pulmonary Arterial Cells through a TGF-β1-Dependent Mechanism

Authors : Clément Bouchet, Guillaume Cardouat, Matthieu Douard, Florence Coste, Paul Robillard, Frédéric Delcambre, Thomas Ducret, Jean-François Quignard, Pierre Vacher, Isabelle Baudrimont, Roger Marthan, Patrick Berger, Christelle Guibert, Véronique Freund-Michel
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July 2022 Biomolecules

Cell Confluence Modulates TRPV4 Channel Activity in Response to Hypoxia

Authors : Solène Barbeau, Alexandre Joushomme, Yann Chappe, Guillaume Cardouat, Isabelle Baudrimont, Véronique Freund-Michel, Christelle Guibert, Roger Marthan, Patrick Berger, Pierre Vacher, Yann Percherancier, Jean-François Quignard, Thomas Ducret
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July 2022 Journal of Allergy and Clinical Immunology

Rhinovirus infection of bronchial epithelium induces specific bronchial smooth muscle cell migration of severe asthmatic patients

Authors : Alexis Celle, Pauline Esteves, Guillaume Cardouat, Fabien Beaufils, Edmée Eyraud, Isabelle Dupin, Elise Maurat, Sabrina Lacomme, Olga Ousova, Hugues Begueret, Matthieu Thumerel, Roger Marthan, Pierre-Olivier Girodet, Patrick Berger, Thomas Trian
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May 2022 Cancer biotherapy & radiopharmaceuticals

Estimation of Cumulative Activity of 177Lu-Cetuximab from a Single Diagnostic 64Cu-Cetuximab Scan.

Authors : Laffon E, Marthan R
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March 2022 Cell Reports

Asthmatic bronchial smooth muscle increases rhinovirus replication within the bronchial epithelium

Authors : Pauline Esteves, Benoit Allard, Alexis Celle, Isabelle Dupin, Elise Maurat, Olga Ousova, Matthieu Thumerel, Jean-William Dupuy, Thierry Leste-Lasserre, Roger Marthan, Pierre-Olivier Girodet, Thomas Trian, Patrick Berger
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February 2022 Revue des Maladies Respiratoires

Implication des canaux mécanosensibles Piezo1 et TRPV4 dans l’hypertension pulmonaire

Authors : S. Barbeau, T. Porto Ribeiro, G. Gilbert, G. Cardouat, I. Baudrimont, V. Freund-Michel, C. Guibert, R. Marthan, P. Vacher, J.-F. Quignard, T. Ducret
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January 2022 Frontiers in Pharmacology

Muscarinic receptor M3 activation promotes fibrocytes contraction

Authors : Henrot, P., Eyraud, E., Maurat, E., Point, S., Cardouat, G., Quignard, J.-F., Esteves, P., Trian, T., Girodet, P.-O., Marthan, R., Zysman, M., Berger, P., Dupin, I.
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January 2022 Nanotoxicology

NiONPs-induced alteration in calcium signaling and mitochondrial function in pulmonary artery endothelial cells involves oxidative stress and TRPV4 channels disruption.

Authors : Germande O, Baudrimont M, Beaufils F, Freund-Michel V, Ducret T, Quignard JF, Errera MH, Lacomme S, Gontier E, Mornet S, Bejko M, Muller B, Baudrimont I
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January 2022 bioRxiv

Short-range interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammatory response

Authors : Eyraud, E., Maurat, E., Sac-Epée, J.-M., Henrot, P., Zysman, M., Esteves, P., Trian, T., Bégueret, H., Girodet, P.-O., Thumerel, M., Hustache-Castaing, R., Marthan, R., Levet, F., Vallois, P., Contin-Bordes, C., Berger, P., Dupin, I.
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December 2021 European Respiratory Journal

Circulating fibrocytes as a new tool to predict lung cancer progression after surgery?

Authors : Pauline Henrot, Fabien Beaufils, Matthieu Thumerel, Edmée Eyraud, Augustin Boudoussier, Hugues Begueret, Elise Maurat, Pierre-Olivier Girodet, Roger Marthan, Patrick Berger, Isabelle Dupin, Maéva Zysman
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September 2021 Biomolecules

Mechanosensitivity in Pulmonary Circulation: Pathophysiological Relevance of Stretch-Activated Channels in Pulmonary Hypertension

Authors : Solène Barbeau, Guillaume Gilbert, Guillaume Cardouat, Isabelle Baudrimont, Véronique Freund-Michel, Christelle Guibert, Roger Marthan, Pierre Vacher, Jean-François Quignard, Thomas Ducret
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September 2021 Cardiovascular toxicology

Effects of FW2 Nanoparticles Toxicity in a New In Vitro Pulmonary Vascular Cells Model Mimicking Endothelial Dysfunction.

Authors : Deweirdt J, Ducret T, Quignard JF, Freund-Michel V, Lacomme S, Gontier E, Muller B, Marthan R, Guibert C, Baudrimont I
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September 2021 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

On Semiquantitative Methods for Assessing Vascular 18F-FDG PET Activity in Large-Vessel Vasculitis.

Authors : Laffon E, Marthan R
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August 2021 EJNMMI research

An abbreviated therapy-dosimetric equation for the companion diagnostic/therapeutic [64/67Cu]Cu-SARTATE.

Authors : Laffon E, de Clermont H, Marthan R
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June 2021 Radiology

Is There a Relevant Imaging Time for Optimal Quantitative 89Zr-DFO-Daratumumab PET Imaging?

Authors : Eric Laffon, Roger Marthan
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June 2021 Cells

Hydrogen Sulfide Metabolism and Pulmonary Hypertension

Authors : Lukas Roubenne, Roger Marthan, Bruno Le Grand, Christelle Guibert
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April 2021 The European respiratory journal

Crucial role of fatty acid oxidation in asthmatic bronchial smooth muscle remodelling.

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April 2021 The Journal of allergy and clinical immunology

Mitochondria are involved in bronchial smooth muscle remodeling in severe preschool wheezers.

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February 2021 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Specific and Nonspecific Uptake in Quantitative 89Zr-Immuno-PET.

Authors : Laffon E, Marthan R
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October 2020 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Automated segmentation of TMTV in DLBCL patients: what about method measurement uncertainty?

Authors : Laffon E, Marthan R
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August 2020 European journal of nuclear medicine and molecular imaging

Is Patlak y-intercept a relevant metrics?

Authors : Laffon E, Marthan R
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May 2020 Archives of toxicology

In vitro study of carbon black nanoparticles on human pulmonary artery endothelial cells: effects on calcium signaling and mitochondrial alterations.

Authors : Deweirdt J, Quignard JF, Lacomme S, Gontier E, Mornet S, Savineau JP, Marthan R, Guibert C, Baudrimont I
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May 2020 European journal of nuclear medicine and molecular imaging

SUR for mediastinal metastatic lymph node status in non-small-cell lung cancer patients.

Authors : Laffon E, Marthan R
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May 2020 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Distribution Volume of [18F]BMS-986192 in NSCLC Patients.

Authors : Laffon E, Marthan R
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March 2020 The European respiratory journal

Connexin-43 is a promising target for pulmonary hypertension due to hypoxaemic lung disease.

Authors :
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January 2020 American journal of physiology. Lung cellular and molecular physiology

Bnip3 as a potential target to treat airway smooth muscle remodeling in asthma?

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January 2020 Haematologica

Prognostic value of 18F-FDG-PET in patients with mantle cell lymphoma: results from the LyMa-PET Project.

Authors : Laffon E, Marthan R
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January 2020 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

SUVmax-V for Assessing Treatment Response in 18F-FDG PET Imaging of Patient-Derived Tumor Xenografts Involving Triple-Negative Breast Cancer.

Authors : Laffon E, Marthan R
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January 2020 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

11C-(+)-PHNO Trapping Reversibility for Quantitative PET Imaging of β-Cell Mass in Patients with Type 1 Diabetes.

Authors : Laffon E, Marthan R
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November 2019 American journal of physiology. Lung cellular and molecular physiology

TRPV4 channel mediates adventitial fibroblast activation and adventitial remodeling in pulmonary hypertension.

Authors : Cussac LA, Cardouat G, Tiruchellvam Pillai N, Campagnac M, Robillard P, Montillaud A, Guibert C, Gailly P, Marthan R, Quignard JF, Savineau JP, Ducret T
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November 2019 Physiology & behavior

Modelling analysis of centroid curves of olfactory habituation in humans.

Authors : Laffon E, Hummel T, Marthan R, Sinding C
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October 2019 European journal of nuclear medicine and molecular imaging

Fitting of late dynamic [18F]MK6240 PET scans for in vivo tau quantification.

Authors : Laffon E, Buj S, de Clermont H, Marthan R
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September 2019 Respiratory research

Determination of reliable lung function parameters in intubated mice.

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September 2019 The European respiratory journal

Fibrocyte accumulation in the airway walls of COPD patients.

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August 2019 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Quantification of 18F-DCFPyL Uptake: TBR versus Patlak’s Analysis.

Authors : Laffon E, de Clermont-Gallerande H, Marthan R
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August 2019 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Reversibility of 68Ga-FAPI-2 trapping might prove an asset for PET quantitative imaging.

Authors : Laffon E, Marthan R
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June 2019 American journal of respiratory cell and molecular biology

Stretch-activated Piezo1 Channel in Endothelial Cells Relaxes Mouse Intrapulmonary Arteries.

Authors : Lhomme A, Gilbert G, Pele T, Deweirdt J, Henrion D, Baudrimont I, Campagnac M, Marthan R, Guibert C, Ducret T, Savineau JP, Quignard JF
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March 2019 EJNMMI research

Correction to: Comparison of three-parameter kinetic model analysis to standard Patlak’s analysis in 18F-FDG PET imaging of lung cancer patients.

Authors : Laffon E, Calcagni ML, Galli G, Giordano A, Capotosti A, Marthan R, Indovina L
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February 2019 International journal of chronic obstructive pulmonary disease

Quantitative CT assessment of bronchial and vascular alterations in severe precapillary pulmonary hypertension.

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February 2019 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Relevance of Measurement Uncertainty for Quantitative Response Assessment of Breast Cancer Bone Metastases with 18F-Fluoride.

Authors : Laffon E, Marthan R
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October 2018

Fibrocyte accumulation in bronchi: a cellular hallmark of COPD

Authors : Isabelle Dupin, Matthieu Thumerel, Elise Maurat, Florence Coste, Hugues Begueret, Thomas Trian, Michel Montaudon, Roger Marthan, Pierre-Olivier Girodet, Patrick Berger
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October 2018 Respiratory medicine

Clinical and economic burden of severe asthma: A French cohort study.

Authors : Nordon C, Grimaldi-Bensouda L, Pribil C, Nachbaur G, Amzal B, Thabut G, Marthan R, Aubier M, COBRA Study Group
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October 2018 European journal of nuclear medicine and molecular imaging

Performance of 18F-FDG PET/MRI and 18F-FDG PET/CT for T and N staging in patients with non-small-cell lung cancer.

Authors : Laffon E, Marthan R
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July 2018 Physiology (Bethesda, Md.)

ORAI Channels as Potential Therapeutic Targets in Pulmonary Hypertension.

Authors : Rode B, Bailey MA, Marthan R, Beech DJ, Guibert C
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July 2018 European journal of nuclear medicine and molecular imaging

Could we avoid computing TMTV of DLBCL patients in routine practice?

Authors : Laffon E, Marthan R
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May 2018 European journal of nuclear medicine and molecular imaging

Optimal method for measuring baseline metabolic tumor volume in DLBCL patients: are statistical agreements of SUV ≥2.5 satisfactory?

Authors : Laffon E, Marthan R
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April 2018 European journal of nuclear medicine and molecular imaging

Should we assess repeatability of PET quantitative uptake measurements of each 18F-labelled tracer?

Authors : Laffon E, de Clermont H, Buj S, Marthan R
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March 2018 Pediatric pulmonology

Montelukast reverses airway remodeling in actively sensitized young mice.

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March 2018 EJNMMI research

Comparison of three-parameter kinetic model analysis to standard Patlak’s analysis in 18F-FDG PET imaging of lung cancer patients.

Authors : Laffon E, Calcagni ML, Galli G, Giordano A, Capotosti A, Marthan R, Indovina L
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February 2018 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

6″-18F-Fluoromaltotriose PET Evaluation in Escherichia Coli-Induced Myositis: Is There Uptake Saturation in Control?

Authors : Laffon E, Marthan R
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November 2017 European journal of nuclear medicine and molecular imaging

On the 18F-fluoride PET imaging quantification to predict 223Ra-dichloride treatment response.

Authors : Laffon E, de Clermont H, Marthan R, Paycha F
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October 2017 Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

A three-time-point method for assessing kinetic parameters of 64Cu-labeled Ramucirumab trapping in VEGFR-2 positive lung tumors.

Authors : Laffon E, Marthan R
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July 2017 Toxicology in vitro : an international journal published in association with BIBRA

Involvement of oxidative stress and calcium signaling in airborne particulate matter – induced damages in human pulmonary artery endothelial cells.

Authors : Deweirdt J, Quignard JF, Crobeddu B, Baeza-Squiban A, Sciare J, Courtois A, Lacomme S, Gontier E, Muller B, Savineau JP, Marthan R, Guibert C, Baudrimont I
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June 2017 Nuclear medicine communications

Measurement uncertainty of lesion and reference mediastinum standardized uptake value in lung cancer.

Authors : Laffon E, Milpied N, Marthan R
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May 2017 Radiology

Allergic Bronchopulmonary Aspergillosis in Cystic Fibrosis: MR Imaging of Airway Mucus Contrasts as a Tool for Diagnosis.

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May 2017 European journal of nuclear medicine and molecular imaging

FDG PET for therapy monitoring in Hodgkin’s and non-Hodgkin’s lymphomas: qPET versus rPET.

Authors : Laffon E, Marthan R
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April 2017 Biochemical pharmacology

T-type voltage gated calcium channels are involved in endothelium-dependent relaxation of mice pulmonary artery.

Authors : Gilbert G, Courtois A, Dubois M, Cussac LA, Ducret T, Lory P, Marthan R, Savineau JP, Quignard JF
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March 2017 Respiratory research

Chronic hypoxia aggravates monocrotaline-induced pulmonary arterial hypertension: a rodent relevant model to the human severe form of the disease.

Authors : Coste F, Guibert C, Magat J, Abell E, Vaillant F, Dubois M, Courtois A, Diolez P, Quesson B, Marthan R, Savineau JP, Muller B, Freund-Michel V
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February 2017 PloS one

Altered vasoreactivity in neonatal rats with pulmonary hypertension associated with bronchopulmonary dysplasia: Implication of both eNOS phosphorylation and calcium signaling.

Authors : Dumas de la Roque E, Smeralda G, Quignard JF, Freund-Michel V, Courtois A, Marthan R, Muller B, Guibert C, Dubois M
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February 2017 Frontiers in physiology

Signaling Pathways Linked to Serotonin-Induced Superoxide Anion Production: A Physiological Role for Mitochondria in Pulmonary Arteries.

Authors : Genet N, Billaud M, Rossignol R, Dubois M, Gillibert-Duplantier J, Isakson BE, Marthan R, Savineau JP, Guibert C
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January 2017 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Cumulated Activity Comparison of 64Cu-/177Lu-Labeled Anti-Epidermal Growth Factor Receptor Antibody in Esophageal Squamous Cell Carcinoma Model.

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December 2016 Toxicology

Calcium signalling induced by in vitro exposure to silicium dioxide nanoparticles in rat pulmonary artery smooth muscle cells.

Authors : Dubes V, Parpaite T, Ducret T, Quignard JF, Mornet S, Reinhardt N, Baudrimont I, Dubois M, Freund-Michel V, Marthan R, Muller B, Savineau JP, Courtois A
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December 2016 Journal of clinical oncology : official journal of the American Society of Clinical Oncology

On the Cutoff of Baseline Total Metabolic Tumor Volume in High-Tumor-Burden Follicular Lymphoma.

Authors : Laffon E, Marthan R
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December 2016 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Repeatability of Quantitative Whole-Body 18F-FDG PET/CT Uptake Measures in Patients with Non-Small Cell Lung Cancer: Dynamic Versus Test-Retest Design.

Authors : Laffon E, Marthan R
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September 2016 Clinical nuclear medicine

Early Assessment of Treatment Response in Takayasu Arteritis: An 18FDG PET Procedure.

Authors : Caubet O, Meunier V, Marthan R, Laffon E
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April 2016 Thorax

CT evaluation of small pulmonary vessels area in patients with COPD with severe pulmonary hypertension.

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April 2016 Pharmacology & therapeutics

Expression and role of connexin-based gap junctions in pulmonary inflammatory diseases.

Authors : Freund-Michel V, Muller B, Marthan R, Savineau JP, Guibert C
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March 2016 American journal of respiratory and critical care medicine

Bronchial Smooth Muscle Remodeling in Nonsevere Asthma.

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March 2016 American journal of physiology. Lung cellular and molecular physiology

Caveolae are involved in mechanotransduction during pulmonary hypertension.

Authors : Gilbert G, Ducret T, Savineau JP, Marthan R, Quignard JF
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January 2016 Toxicology in vitro : an international journal published in association with BIBRA

Involvement of Heme Oxygenase-1 in particulate matter-induced impairment of NO-dependent relaxation in rat intralobar pulmonary arteries.

Authors : Barrier M, Bégorre MA, Baudrimont I, Dubois M, Freund-Michel V, Marthan R, Savineau JP, Muller B, Courtois A
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January 2016 Ultrasound in medicine & biology

Vital Capacity Impairment due to Neuromuscular Disease and its Correlation with Diaphragmatic Ultrasound: A Preliminary Study.

Authors : Carrié C, Bonnardel E, Vally R, Revel P, Marthan R, Marthan R
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December 2015 The Journal of allergy and clinical immunology

Selective dysfunction of p53 for mitochondrial biogenesis induces cellular proliferation in bronchial smooth muscle from asthmatic patients.

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December 2015 American journal of respiratory and critical care medicine

Excess Risk of Cancer from Computed Tomography Scan Is Small but Not So Low as to Be Incalculable.

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November 2015 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

SUVpeak Performance in Lung Cancer: Comparison to Average SUV from the 40 Hottest Voxels.

Authors : Laffon E, Burger IA, Lamare F, de Clermont H, Marthan R
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October 2015 The Journal of allergy and clinical immunology

Blood fibrocytes are recruited during acute exacerbations of chronic obstructive pulmonary disease through a CXCR4-dependent pathway.

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August 2015 American journal of respiratory and critical care medicine

Role of Nerve Growth Factor in Development and Persistence of Experimental Pulmonary Hypertension.

Authors : Freund-Michel V, Cardoso Dos Santos M, Guignabert C, Montani D, Phan C, Coste F, Tu L, Dubois M, Girerd B, Courtois A, Humbert M, Savineau JP, Muller B
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June 2015 Annals of surgery

Total Lesion Glycolysis in Early-stage Non-small Cell Lung Cancer: Proposal for an Alternative Dimensionless Volume-based Parameter.

Authors : Laffon E, Marthan R
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May 2015 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Simplified Methods for Quantification of 18F-Fluoromethylcholine Uptake: Is SUVAUC,PP Actually an SUV?

Authors : Laffon E, de Clermont H, Marthan R
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May 2015 The Lancet. Oncology

PET-adapted salvage therapy for Hodgkin’s lymphoma.

Authors : Laffon E, Marthan R
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April 2015 American Journal of Respiratory and Critical Care Medicine

Calcium channel blocker reduces airway remodeling in severe asthma. A proof-of-concept study.

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April 2015 Nuclear medicine and biology

The total amount of uptake may affect the input function: a theoretic approach about 18F-FDG PET imaging.

Authors : Laffon E, Marthan R
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March 2015 PloS one

An age-wise comparison of human airway smooth muscle proliferative capacity.

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March 2015 American journal of respiratory and critical care medicine

House dust mites induce proliferation of severe asthmatic smooth muscle cells via an epithelium-dependent pathway.

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March 2015 Pflugers Archiv : European journal of physiology

Effect of hypoxia on TRPV1 and TRPV4 channels in rat pulmonary arterial smooth muscle cells.

Authors : Parpaite T, Cardouat G, Mauroux M, Gillibert-Duplantier J, Robillard P, Quignard JF, Marthan R, Savineau JP, Ducret T
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February 2015 Journal of cell science

Human FAM154A (SAXO1) is a microtubule-stabilizing protein specific to cilia and related structures.

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February 2015 Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Quantitative positron emission tomography imaging for response assessment of [18F]fluorodeoxyglucose-avid lymphomas: should we report standard uptake value confidence limits?

Authors : Laffon E, Marthan R
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January 2015 American journal of respiratory and critical care medicine

Computed tomographic measurement of airway remodeling and emphysema in advanced chronic obstructive pulmonary disease. Correlation with pulmonary hypertension.

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December 2014 Medical physics

Comment on “Correction for FDG PET dose extravasations: Monte Carlo validation and quantitative evaluation of patient studies” [Med. Phys. 41, 052502 (2014)].

Authors : Buj S, Tendero K, Marthan R, Laffon E
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November 2014 Radiology

Prognostic value of mean standardized uptake value in patients with stage I non-small cell lung cancer treated with stereotactic body radiation therapy.

Authors : Laffon E, Marthan R
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October 2014 European journal of nuclear medicine and molecular imaging

Liver SUV versus stage in Hodgkin’s lymphoma: the total amount of uptake may play a role in the inverse relationship.

Authors : Laffon E, de Clermont H, Lamare F, Marthan R
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August 2014 European journal of nuclear medicine and molecular imaging

Interim FDG PET scans in lymphoma: SUV measurement error may impair qPET methodology.

Authors : Laffon E, Marthan R
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July 2014 Cardiovascular research

T-type calcium channels are involved in hypoxic pulmonary hypertension.

Authors : Chevalier M, Gilbert G, Roux E, Lory P, Marthan R, Savineau JP, Quignard JF
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June 2014 Transplantation proceedings

Impact of donor-to-recipient weight ratio on survival after bilateral lung transplantation.

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June 2014 Nuclear medicine and biology

Estimating the amount of FDG uptake in physiological tissues.

Authors : Laffon E, de Clermont H, Lamare F, Marthan R
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June 2014 European radiology

Variability of average SUV from several hottest voxels is lower than that of SUVmax and SUVpeak.

Authors : Laffon E, Lamare F, de Clermont H, Burger IA, Marthan R
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May 2014 The Journal of allergy and clinical immunology

Bronchi wall and lumen volumes to assess airway remodeling in asthma by using CT: an innovative method?

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April 2014 Cardiovascular research

Stretch-induced Ca2+ signalling in vascular smooth muscle cells depends on Ca2+ store segregation.

Authors : Gilbert G, Ducret T, Marthan R, Savineau JP, Quignard JF
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February 2014 PloS one

Protease activated receptor-2 expression and function in asthmatic bronchial smooth muscle.

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November 2013 PloS one

Biopterin metabolism and eNOS expression during hypoxic pulmonary hypertension in mice.

Authors : Dubois M, Delannoy E, Duluc L, Closs E, Li H, Toussaint C, Gadeau AP, Gödecke A, Freund-Michel V, Courtois A, Marthan R, Savineau JP, Muller B
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August 2013 Journal of nuclear medicine technology

Variability of total lesion glycolysis by 18F-FDG-positive tissue thresholding in lung cancer.

Authors : Laffon E, de Clermont H, Lamare F, Marthan R
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August 2013 Molecular imaging and biology

Dynamic changes of 18F-FDG uptake in normal lung: probing a predictive model analysis.

Authors : Laffon E, Marthan R
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July 2013 Journal of applied toxicology : JAT

Characterization of the components of urban particulate matter mediating impairment of nitric oxide-dependent relaxation in intrapulmonary arteries.

Authors : Courtois A, Prouillac C, Baudrimont I, Ohayon-Courtes C, Freund-Michel V, Dubois M, Lisbonne-Autissier M, Marthan R, Savineau JP, Muller B
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May 2013 Pediatric research

Beneficial effect of dehydroepiandrosterone on pulmonary hypertension in a rodent model of pulmonary hypertension in infants.

Authors : Dumas de la Roque E, Quignard JF, Ducret T, Dahan D, Courtois A, Begueret H, Marthan R, Savineau JP
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April 2013 EJNMMI research

Calculating an estimate of tissue integrated activity in 18F-FDG PET imaging using one SUV value.

Authors : Laffon E, Bardiès M, Barbet J, Marthan R
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January 2013 Therapeutic advances in respiratory disease

Reactive oxygen species as therapeutic targets in pulmonary hypertension.

Authors : Freund-Michel V, Guibert C, Dubois M, Courtois A, Marthan R, Savineau JP, Muller B
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December 2012 Biochemical pharmacology

Role of DHEA in cardiovascular diseases.

Authors : Savineau JP, Marthan R, Dumas de la Roque E
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November 2012 American journal of respiratory cell and molecular biology

Ca(2+)-activated K(+) channel-3.1 blocker TRAM-34 attenuates airway remodeling and eosinophilia in a murine asthma model.

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October 2012 PloS one

In vivo micro-CT assessment of airway remodeling in a flexible OVA-sensitized murine model of asthma.

Authors : Lederlin M, Ozier A, Dournes G, Ousova O, Girodet PO, Begueret H, Marthan R, Montaudon M, Laurent F, Berger P
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October 2012 European radiology

Variability of ¹⁸F-FDG-positive lung lesion volume by thresholding.

Authors : Laffon E, de Clermont H, Marthan R
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September 2012

Comments on Point:Counterpoint: Alterations in airway smooth muscle phenotype do/do not cause airway hyperresponsiveness in asthma.

Authors : Bosse Y, Vagula MC, Rawding RS, Pun M, Black JL, Burgess J, Oliver B, Berger P, Marthan R, Adner M
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September 2012 American journal of physiology. Lung cellular and molecular physiology

Implication of the ryanodine receptor in TRPV4-induced calcium response in pulmonary arterial smooth muscle cells from normoxic and chronically hypoxic rats.

Authors : Dahan D, Ducret T, Quignard JF, Marthan R, Savineau JP, Estève E
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July 2012 Pflugers Archiv : European journal of physiology

Involvement of TRPV1 and TRPV4 channels in migration of rat pulmonary arterial smooth muscle cells.

Authors : Martin E, Dahan D, Cardouat G, Gillibert-Duplantier J, Marthan R, Savineau JP, Ducret T
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June 2012 Journal of nuclear medicine : official publication, Society of Nuclear Medicine

18F-FDG uptake to assess eosinophilic inflammation in asthma: would SUV at late imaging be relevant?

Authors : Laffon E, Marthan R
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May 2012 Pediatric pulmonology

Effect of high-frequency oscillation and percussion versus conventional ventilation in a piglet model of meconium aspiration.

Authors : Renesme L, Elleau C, Nolent P, Fayon M, Marthan R, Dumas De La Roque E
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April 2012 The European respiratory journal

Dehydroepiandrosterone reverses chronic hypoxia/reoxygenation-induced right ventricular dysfunction in rats.

Authors : Dumas de La Roque E, Bellance N, Rossignol R, Begueret H, Billaud M, dos Santos P, Ducret T, Marthan R, Dahan D, Ramos-Barbón D, Amor-Carro Ó, Fayon M
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March 2012 Biochemical pharmacology

Dehydroepiandrosterone (DHEA) inhibits voltage-gated T-type calcium channels.

Authors : Chevalier M, Gilbert G, Lory P, Marthan R, Quignard JF, Savineau JP
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January 2012 American journal of respiratory and critical care medicine

Role of YKL-40 in bronchial smooth muscle remodeling in asthma.

Authors :
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January 2012 Annales d'endocrinologie

Dehydroepiandrosterone (DHEA) improves pulmonary hypertension in chronic obstructive pulmonary disease (COPD): a pilot study.

Authors : Dumas de La Roque E, Savineau JP, Metivier AC, Billes MA, Kraemer JP, Doutreleau S, Jougon J, Marthan R, Moore N, Fayon M, Baulieu EÉ, Dromer C
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October 2011 Journal of vascular research

Development and characterization of an animal model of severe pulmonary arterial hypertension.

Authors : Morimatsu Y, Sakashita N, Komohara Y, Ohnishi K, Masuda H, Dahan D, Takeya M, Guibert C, Marthan R
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August 2011 Journal of nuclear medicine technology

Is liver SUV stable over time in ¹⁸F-FDG PET imaging?

Authors : Laffon E, Adhoute X, de Clermont H, Marthan R
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July 2011 European radiology

A method of adjusting SUV for injection-acquisition time differences in (18)F-FDG PET imaging.

Authors : Laffon E, de Clermont H, Marthan R
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April 2011 Molecular imaging and biology

Feasibility of assessing [(18)F]FDG lung metabolism with late dynamic PET imaging.

Authors : Laffon E, de Clermont H, Vernejoux JM, Jougon J, Marthan R
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March 2011

[Pathophysiology of asthma].

Authors : Ozier A, Bara I, Girodet PO, Marthan R, Berger P
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March 2011 Revue des maladies respiratoires

[COPD and inflammation: Statement from a French expert group. How to treat inflammation?].

Authors : Roche N, Devillier P, Aguilaniu B, Escamilla R, Wallaert B, Burgel PR, Berger P, Brillet PY, Chambellan A, Chanez P, Chaouat A, Louis R, Mal H, Aubier M
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March 2011 Respiratory research

Role of the gap junctions in the contractile response to agonists in pulmonary artery from two rat models of pulmonary hypertension.

Authors : Billaud M, Dahan D, Marthan R, Savineau JP, Guibert C
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February 2011 Pharmacology & therapeutics

Airway remodeling in asthma: new mechanisms and potential for pharmacological intervention.

Authors : Girodet PO, Ozier A, Bara I, Tunon de Lara JM, Marthan R, Berger P
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February 2011 Respiratory medicine

Control maintenance can be predicted by exhaled NO monitoring in asthmatic patients.

Authors : Ozier A, Girodet PO, Bara I, Tunon de Lara JM, Marthan R, Berger P
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February 2011 Revue des maladies respiratoires

[COPD and inflammation: statement from a French expert group. Phenotypes related to inflammation].

Authors : Perez T, Mal H, Aguilaniu B, Brillet PY, Chaouat A, Louis R, Muir JF, Similowski T, Berger P, Burgel PR, Chambellan A, Chanez P, Devillier P, Roche N
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January 2011

The pivotal role of airway smooth muscle in asthma pathophysiology.

Authors : Ozier A, Allard B, Bara I, Girodet PO, Trian T, Marthan R, Berger P
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January 2011 EUROPEAN RESPIRATORY REVIEW

Beyond corticosteroids: future prospects in the management of inflammation in COPD

Authors :
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January 2011 Canadian journal of physiology and pharmacology

Chronic hypoxia-induced alterations in mitochondrial energy metabolism are not reversible in rat heart ventricles.

Authors : Nouette-Gaulain K, Biais M, Savineau JP, Marthan R, Mazat JP, Letellier T, Sztark F
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December 2010 Cancer biotherapy & radiopharmaceuticals

Kinetic model analysis for absorbed dose calculation applied to brain in [¹⁸F]-fluorodeoxyglucose positron emission tomography imaging.

Authors : Laffon E, Bardiès M, Barbet J, Marthan R
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November 2010 Revue des maladies respiratoires

[COPD and inflammation: statement from a French expert group: inflammation and remodelling mechanisms].

Authors : Aubier M, Marthan R, Berger P, Chambellan A, Chanez P, Aguilaniu B, Brillet PY, Burgel PR, Chaouat A, Devillier P, Escamilla R, Louis R, Mal H, Roche N
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October 2010 Cell calcium

Stretch-activated channels in pulmonary arterial smooth muscle cells from normoxic and chronically hypoxic rats.

Authors : Ducret T, El Arrouchi J, Courtois A, Quignard JF, Marthan R, Savineau JP
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October 2010 NMR in biomedicine

Effect of chronic hypoxia on pulmonary artery blood velocity in rats as assessed by electrocardiography-triggered three-dimensional time-resolved MR angiography.

Authors : de La Roque ED, Thiaudière E, Ducret T, Marthan R, Franconi JM, Guibert C, Parzy E
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March 2010 Toxicology and applied pharmacology

Effect of engineered nanoparticles on vasomotor responses in rat intrapulmonary artery.

Authors : Courtois A, Andujar P, Ladeiro Y, Ducret T, Rogerieux F, Lacroix G, Baudrimont I, Guibert C, Roux E, Canal-Raffin M, Brochard P, Marano F, Marthan R, Muller B
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February 2010 Allergy

Mast cell adhesion to bronchial smooth muscle in asthma specifically depends on CD51 and CD44 variant 6.

Authors :
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January 2010 EUROPEAN RESPIRATORY JOURNAL

Pathophysiology of bronchial smooth muscle remodelling in asthma

Authors :
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September 2009 Radiology

Bronchial measurements in patients with asthma: comparison of quantitative thin-section CT findings with those in healthy subjects and correlation with pathologic findings.

Authors : Montaudon M, Lederlin M, Reich S, Begueret H, Tunon-de-Lara JM, Marthan R, Berger P, Laurent F
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August 2009 European radiology

Airway remodeling in a mouse asthma model assessed by in-vivo respiratory-gated micro-computed tomography.

Authors : Lederlin M, Ozier A, Montaudon M, Begueret H, Ousova O, Marthan R, Berger P, Laurent F
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August 2009 Cardiovascular research

Hypoxia-induced hyperreactivity of pulmonary arteries: role of cyclooxygenase-2, isoprostanes, and thromboxane receptors.

Authors : Delannoy E, Courtois A, Freund-Michel V, Leblais V, Marthan R, Muller B
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July 2009 PloS one

Vascular smooth muscle modulates endothelial control of vasoreactivity via reactive oxygen species production through myoendothelial communications.

Authors : Billaud M, Marthan R, Savineau JP, Guibert C
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June 2009 Nuclear medicine communications

Assessment of dual-time-point 18F-FDG-PET imaging for pulmonary lesions.

Authors :
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June 2009 The European respiratory journal

Signalling pathways involved in the contractile response to 5-HT in the human pulmonary artery.

Authors : Rodat-Despoix L, Aires V, Ducret T, Marthan R, Savineau JP, Rousseau E, Guibert C
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May 2009 Journal of nuclear medicine technology

Is the physical decay correction of the (18)F-FDG input function in dynamic PET imaging justified?

Authors : Laffon E, Barret O, Marthan R, Ducassou D
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February 2009 Journal of magnetic resonance imaging : JMRI

Transit-time method to demonstrate whether or not an impedance matching occurs at the pulmonary junction.

Authors : Laffon E, Laurent F, Ducassou D, Marthan R
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January 2009 European radiology

Bronchial morphometry in smokers: comparison with healthy subjects by using 3D CT.

Authors : Montaudon M, Berger P, Lederlin M, Marthan R, Tunon-de-Lara JM, Laurent F
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November 2008 Journal of nuclear medicine technology

The effect of renal failure on 18F-FDG uptake: a theoretic assessment.

Authors : Laffon E, Cazeau AL, Monet A, de Clermont H, Fernandez P, Marthan R, Ducassou D
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May 2008 Environmental health perspectives

Impairment of NO-dependent relaxation in intralobar pulmonary arteries: comparison of urban particulate matter and manufactured nanoparticles.

Authors : Courtois A, Andujar P, Ladeiro Y, Baudrimont I, Delannoy E, Leblais V, Begueret H, Galland MA, Brochard P, Marano F, Marthan R, Muller B
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December 2007 The Journal of experimental medicine

Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma.

Authors :
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November 2007 Journal of vascular research

Heterogeneity in 5-HT-induced contractile and proliferative responses in rat pulmonary arterial bed.

Authors : Rodat-Despoix L, Crevel H, Marthan R, Savineau JP, Guibert C
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October 2007 Journal of anatomy

Assessment of bronchial wall thickness and lumen diameter in human adults using multi-detector computed tomography: comparison with theoretical models.

Authors : Montaudon M, Desbarats P, Berger P, de Dietrich G, Marthan R, Laurent F
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July 2007 Cell calcium

Serotonin-induced activation of TRPV4-like current in rat intrapulmonary arterial smooth muscle cells.

Authors : Ducret T, Guibert C, Marthan R, Savineau JP
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February 2007 Allergy

Omalizumab decreases nonspecific airway hyperresponsiveness in vitro.

Authors : Berger P, Scotto-Gomez E, Molimard M, Marthan R, Le Gros V, Tunon-de-Lara JM
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January 2007 Current pharmaceutical design

Modulation of ion channels in pulmonary arterial hypertension.

Authors : Guibert C, Marthan R, Savineau JP
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May 2004 American journal of physiology. Lung cellular and molecular physiology

Store-operated calcium entry and intracellular calcium release channels in airway smooth muscle.

Authors : Marthan R
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January 2004 American journal of physiology. Lung cellular and molecular physiology

5-HT induces an arachidonic acid-sensitive calcium influx in rat small intrapulmonary artery.

Authors : Guibert C, Marthan R, Savineau JP
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January 2004 The Journal of pharmacology and experimental therapeutics

Role of alpha-adrenergic receptors in the effect of the beta-adrenergic receptor ligands, CGP 12177, bupranolol, and SR 59230A, on the contraction of rat intrapulmonary artery.

Authors : Leblais V, Pourageaud F, Ivorra MD, Guibert C, Marthan R, Muller B
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November 2003

Tryptase-stimulated human airway smooth muscle cells induce cytokine synthesis and mast cell chemotaxis.

Authors : Berger P, Girodet PO, Begueret H, Ousova O, Perng DW, Marthan R, Walls AF, Tunon de Lara JM
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November 2003 European radiology

Quantitative MRI comparison of systemic hemodynamics in Mustard/Senning repaired patients and healthy volunteers at rest.

Authors : Laffon E, Jimenez M, Latrabe V, Ducassou D, Choussat A, Marthan R, Laurent F
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November 2003 Revue des maladies respiratoires

[Exercise testing in respiratory medicine]

Authors : Marthan R
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September 2003 Muscle & nerve

A prospective evaluation of phrenic nerve conduction in multifocal motor neuropathy and chronic inflammatory demyelinating polyneuropathy.

Authors : Macia F, Le Masson G, Rouanet-Larriviere M, Habonimana D, Ferrer X, Marthan R, Lagueny A
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August 2003 Journal of applied physiology (Bethesda, Md. : 1985)

A computed method for noninvasive MRI assessment of pulmonary arterial hypertension.

Authors : Laffon E, Vallet C, Bernard V, Montaudon M, Ducassou D, Laurent F, Marthan R
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August 2003 Physiological measurement

MRI quantification of the role of the reflected pressure wave on coronary and ascending aortic blood flow.

Authors : Laffon E, Galy-Lacour C, Laurent F, Ducassou D, Marthan R
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July 2003 Proceedings of the National Academy of Sciences of the United States of America

Dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary hypertension.

Authors : Bonnet S, Dumas-de-La-Roque E, Bégueret H, Marthan R, Fayon M, Dos Santos P, Savineau JP, Baulieu EE
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June 2003 Pediatric pulmonology

Montelukast does not protect against hyperoxia-induced inhibition of alveolarization in newborn rats.

Authors : Jouvencel P, Fayon M, Choukroun ML, Carles D, Montaudon D, Dumas E, Begueret H, Marthan R
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June 2003 British journal of pharmacology

Effect of sildenafil on cyclic nucleotide phosphodiesterase activity, vascular tone and calcium signaling in rat pulmonary artery.

Authors : Pauvert O, Lugnier C, Keravis T, Marthan R, Rousseau E, Savineau JP
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May 2003 Radiology

Structure and function of small airways in smokers: relationship between air trapping at CT and airway inflammation.

Authors : Berger P, Laurent F, Begueret H, Perot V, Rouiller R, Raherison C, Molimard M, Marthan R, Tunon-de-Lara JM
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April 2003 The Journal of biological chemistry

Heme oxygenase inhibits human airway smooth muscle proliferation via a bilirubin-dependent modulation of ERK1/2 phosphorylation.

Authors : Taillé C, Almolki A, Benhamed M, Zedda C, Mégret J, Berger P, Lesèche G, Fadel E, Yamaguchi T, Marthan R, Aubier M, Boczkowski J
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April 2003 Anesthesia and analgesia

The effects of propofol and etomidate on airway contractility in chronically hypoxic rats.

Authors : Ouédraogo N, Marthan R, Roux E
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December 2002

[The pathophysiological role of smooth muscle cells in bronchial inflammation]

Authors : Berger P, Marthan R, Tunon de Lara JM
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December 2002 Anesthesiology

Effects of bupivacaine on mitochondrial energy metabolism in heart of rats following exposure to chronic hypoxia.

Authors : Nouette-Gaulain K, Forestier F, Malgat M, Marthan R, Mazat JP, Sztark F
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September 2002 American journal of physiology. Lung cellular and molecular physiology

Combined effect of chronic hypoxia and in vitro exposure to gas pollutants on airway reactivity.

Authors : Roux E, Duvert M, Marthan R
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July 2002 Allergy

Passive sensitization of human airways induces mast cell degranulation and release of tryptase.

Authors : Berger P, N'guyen C, Buckley M, Scotto-Gomez E, Marthan R, Tunon-de-Lara JM
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June 2002 Pediatric pulmonology

Differential effect of dexamethasone and hydrocortisone on alveolar growth in rat pups.

Authors : Fayon M, Jouvencel P, Carles D, Choukroun ML, Marthan R
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May 2002 Biochemical pharmacology

Characterisation of cyclic nucleotide phosphodiesterase isoforms in the media layer of the main pulmonary artery.

Authors : Pauvert O, Salvail D, Rousseau E, Lugnier C, Marthan R, Savineau JP
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March 2002 Cardiovascular research

Reversal of chronic hypoxia-induced alterations in pulmonary artery smooth muscle electromechanical coupling upon air breathing.

Authors : Bonnet S, Dubuis E, Vandier C, Martin S, Marthan R, Savineau JP
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February 2002 Pediatric pulmonology

Pharmacologically induced relaxation of tracheal smooth muscle is increased in hyperoxia-exposed 15-day-old rats.

Authors : Fayon MJ, Denis D, Molimard M, Berger P, Choukroun ML, Demarquez JL, Marthan R, Clevel H, Lachaud JL, Martinez B, Téchoueyres P
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January 2002 Cell biology and toxicology

In vitro effect of air pollutants on human bronchi.

Authors : Roux E, Ouedraogo N, Hyvelin JM, Savineau JP, Marthan R
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September 2001

Tryptase and agonists of PAR-2 induce the proliferation of human airway smooth muscle cells.

Authors : Berger P, Perng DW, Thabrew H, Compton SJ, Cairns JA, McEuen AR, Marthan R, Tunon De Lara JM, Walls AF
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August 2001

Selected contribution: tryptase-induced PAR-2-mediated Ca(2+) signaling in human airway smooth muscle cells.

Authors : Berger P, Tunon-De-Lara JM, Savineau JP, Marthan R
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July 2001 American journal of physiology. Lung cellular and molecular physiology

Effect of chronic hypoxia on agonist-induced tone and calcium signaling in rat pulmonary artery.

Authors : Bonnet S, Belus A, Hyvelin JM, Roux E, Marthan R, Savineau JP
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July 2001 American journal of physiology. Lung cellular and molecular physiology

Chronic hypoxia-induced spontaneous and rhythmic contractions in the rat main pulmonary artery.

Authors : Bonnet S, Hyvelin JM, Bonnet P, Marthan R, Savineau JP
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June 2001 Journal of applied physiology (Bethesda, Md. : 1985)

Noninvasive assessment of pulmonary arterial hypertension by MR phase-mapping method.

Authors : Laffon E, Laurent F, Bernard V, De Boucaud L, Ducassou D, Marthan R
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February 2001 Journal of applied physiology (Bethesda, Md. : 1985)

Selected contribution: effect of the aldehyde acrolein on acetylcholine-induced membrane current in airway smooth muscle cells.

Authors : Hyvelin JM, Savineau JP, Marthan R
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February 2001 Journal of applied physiology (Bethesda, Md. : 1985)

Tuning of pulmonary arterial circulation evidenced by MR phase mapping in healthy volunteers.

Authors : Laffon E, Bernard V, Montaudon M, Marthan R, Barat JL, Laurent F
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January 2001 PEDIATRIC RESEARCH

Prolonged moderate hyperoxia induces hyperresponsiveness and airway inflammation in newborn rats

Authors :
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November 2000 British journal of pharmacology

Role of EDHF in the vasodilatory effect of loop diuretics in guinea-pig mesenteric resistance arteries.

Authors : Pourageaud F, Bappel-Gozalbes C, Marthan R, Freslon JL
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August 2000 American journal of respiratory and critical care medicine

Human isolated bronchial smooth muscle contains functional ryanodine/caffeine-sensitive Ca-release channels.

Authors : Hyvelin JM, Martin C, Roux E, Marthan R, Savineau JP
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July 2000 Fundamental & clinical pharmacology

Interaction of extracellular albumin and intravenous anaesthetics, etomidate and propofol, on calcium signalling in rat airway smooth muscle cells.

Authors : Belouchi NE, Roux E, Savineau JP, Marthan R
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June 2000 Cell calcium

NO-induced modulation of calcium-oscillations in pulmonary vascular smooth muscle.

Authors : Pauvert O, Marthan R, Savineau J
Read more
June 2000 Revue des maladies respiratoires

[Genetic polymorphism and asthma]

Authors : Molimard M, Marthan R
Read more
June 2000 Revue des maladies respiratoires

[Special characteristics of bronchial smooth muscle cells]

Authors : Marthan R, Molimard M
Read more
June 2000 Revue des maladies respiratoires

[In vitro techniques for the study of muscle contractility]

Authors : Advenier C, Naline E, Molimard M, Marthan R
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April 2000 Toxicology and applied pharmacology

Cellular mechanisms of acrolein-induced alteration in calcium signaling in airway smooth muscle.

Authors : Hyvelin JM, Roux E, Prévost MC, Savineau JP, Marthan R
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February 2000 News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Cytosolic Calcium Oscillations in Smooth Muscle Cells.

Authors : Savineau JP, Marthan R
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January 2000 European radiology

Functional significance of air trapping detected in moderate asthma.

Authors : Laurent F, Latrabe V, Raherison C, Marthan R, Tunon-de-Lara JM
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January 2000 Life sciences

Cellular mechanisms involved in iso-osmotic high K+ solutions-induced contraction of the estrogen-primed rat myometrium.

Authors : Trujillo MM, Ausina P, Savineau JP, Marthan R, Strippoli G, Advenier C, Pinto FM, Candenas ML
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August 1999 The American journal of physiology

Pregnant rat myometrial cells show heterogeneous ryanodine- and caffeine-sensitive calcium stores.

Authors : Martin C, Hyvelin JM, Chapman KE, Marthan R, Ashley RH, Savineau JP
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August 1999 American journal of respiratory and critical care medicine

Human isolated airway contraction: interaction between air pollutants and passive sensitization.

Authors : Roux E, Hyvelin JM, Savineau JP, Marthan R
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July 1999 The European respiratory journal

Effect of chronic hypoxia on calcium signalling in airway smooth muscle cells.

Authors : Belouchi NE, Roux E, Savineau JP, Marthan R
Read more
June 1999

Mast cell tryptase as a mediator of hyperresponsiveness in human isolated bronchi.

Authors : Berger P, Compton SJ, Molimard M, Walls AF, N'Guyen C, Marthan R, Tunon-De-Lara JM
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April 1999 AJR. American journal of roentgenology

Pneumothoraces and chest tube placement after CT-guided transthoracic lung biopsy using a coaxial technique: incidence and risk factors.

Authors : Laurent F, Michel P, Latrabe V, Tunon de Lara M, Marthan R
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January 1999 EUROPEAN RESPIRATORY JOURNAL

Assessment of bronchial inflammation using an automated cell recognition system based on colour analysis

Authors :
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January 1999 Therapie

[Electrophysiology and calcium signalling in human bronchial smooth muscle]

Authors : Marthan R, Hyvelin JM, Roux E, Savineau JP
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January 1999 Bulletin de l'Academie nationale de medecine

[Cellular pathophysiologic effects of various air pollutants on the airways]

Authors : Marthan R
Read more
September 1998 Electromyography and clinical neurophysiology

Study of central and peripheral conductions to the diaphragm in 22 patients with definite multiple sclerosis.

Authors : Lagueny A, Arnaud A, Le Masson G, Burbaud P, Deliac P, Marthan R
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September 1998 American journal of respiratory cell and molecular biology

Calcium signaling in airway smooth muscle cells is altered by in vitro exposure to the aldehyde acrolein.

Authors : Roux E, Hyvelin JM, Savineau JP, Marthan R
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September 1998 General pharmacology

Muscarinic stimulation of airway smooth muscle cells.

Authors : Roux E, Molimard M, Savineau JP, Marthan R
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August 1998 The American journal of physiology

Cellular mechanisms and role of endothelin-1-induced calcium oscillations in pulmonary arterial myocytes.

Authors : Hyvelin JM, Guibert C, Marthan R, Savineau JP
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June 1998 Revue des maladies respiratoires

[Leukotrienes and airway smooth muscle]

Authors : Marthan R
Read more
February 1998 American journal of respiratory and critical care medicine

Immunoglobulin E-induced passive sensitization of human airways: an immunohistochemical study.

Authors : Berger P, Walls AF, Marthan R, Tunon-de-Lara JM
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February 1998 Anesthesiology

Effects of intravenous anesthetics on normal and passively sensitized human isolated airway smooth muscle.

Authors : Ouedraogo N, Roux E, Forestier F, Rossetti M, Savineau JP, Marthan R
Read more
January 1998 Revue de pneumologie clinique

[Genetic polymorphism of adrenergic beta 2 receptors]

Authors : Marthan R
Read more
June 1997 Cell calcium

Oscillatory Cl- current induced by angiotensin II in rat pulmonary arterial myocytes: Ca2+ dependence and physiological implication.

Authors : Guibert C, Marthan R, Savineau JP
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April 1997 British journal of pharmacology

[Ca2+]i oscillations induced by muscarinic stimulation in airway smooth muscle cells: receptor subtypes and correlation with the mechanical activity.

Authors : Roux E, Guibert C, Savineau JP, Marthan R
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January 1997 Fundamental & clinical pharmacology

Modulation of the calcium sensitivity of the smooth muscle contractile apparatus: molecular mechanisms, pharmacological and pathophysiological implications.

Authors : Savineau JP, Marthan R
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December 1996 Cell biology and toxicology

Human bronchial smooth muscle responsiveness after in vitro exposure to oxidizing pollutants.

Authors : Marthan R, Roux E, Savineau JP
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December 1996 The European respiratory journal

Pulmonary gas exchange in elderly subjects.

Authors : Guénard H, Marthan R
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October 1996 The American journal of physiology

Human and rat airway smooth muscle responsiveness after ozone exposure in vitro.

Authors : Roux E, Guibert C, Crevel H, Savineau JP, Marthan R
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September 1996 The American journal of physiology

Effect of extracellular ATP on cytosolic Ca2+ concentration in rat pulmonary artery myocytes.

Authors : Guibert C, Pacaud P, Loirand G, Marthan R, Savineau JP
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June 1996 Pulmonary pharmacology

Effect of modulators of tyrosine kinase activity on agonist-induced contraction in the rat pulmonary vascular smooth muscle.

Authors : Savineau JP, Gonzalez De La Fuente P, Marthan R
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May 1996 The European respiratory journal

Airway circulation in health and disease.

Authors : Lockhart A, Marthan R, Charan N, Paré P
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April 1996 The American journal of physiology

Angiotensin II-induced Ca(2+)-oscillations in vascular myocytes from the rat pulmonary artery.

Authors : Guibert C, Marthan R, Savineau JP
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February 1996 Transplantation proceedings

Improvement of brain-dead lung assessment based on the mechanical properties of the respiratory system.

Authors : Labrousse L, Sztark F, Kays C, Thicoïpe M, Lassié P, Couraud L, Marthan R
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November 1995 The European respiratory journal

IgE-induced passive sensitization of human isolated bronchi and lung mast cells.

Authors : Tunon de Lara JM, Okayama Y, Savineau JP, Marthan R
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June 1995 The American journal of physiology

Role of protein kinase C in nonsensitized and passively sensitized human isolated bronchial smooth muscle.

Authors : Rossetti M, Savineau JP, Crevel H, Marthan R
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March 1995 Pflugers Archiv : European journal of physiology

Control of pulmonary vascular smooth muscle tone by sarcoplasmic reticulum Ca2+ pump blockers: thapsigargin and cyclopiazonic acid.

Authors : Gonzalez De La Fuente P, Savineau JP, Marthan R
Read more
February 1995 Respiration physiology

Cellular mechanisms of hypoxia-induced contraction in human and rat pulmonary arteries.

Authors : Savineau JP, Gonzalez de la Fuente P, Marthan R
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August 1994 The American journal of physiology

Human airway smooth muscle responsiveness in neonatal lung specimens.

Authors : Fayon M, Ben-Jebria A, Elleau C, Carles D, Demarquez JL, Savineau JP, Marthan R
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April 1994 British journal of pharmacology

Diosmin-induced increase in sensitivity to Ca2+ of the smooth muscle contractile apparatus in the rat isolated femoral vein.

Authors : Savineau JP, Marthan R
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February 1994 The Journal of physiology

Activation properties of chemically skinned fibres from human isolated bronchial smooth muscle.

Authors : Savineau JP, Marthan R
Read more
February 1994 Muscle & nerve

Single fiber EMG and spectral analysis of surface EMG in myotonia congenita with or without transient weakness.

Authors : Lagueny A, Marthan R, Schuermans P, Le Collen P, Ferrer X, Julien J
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February 1994 American journal of respiratory and critical care medicine

Human bronchial smooth muscle responsiveness after in vitro exposure to acrolein.

Authors : Ben-Jebria A, Marthan R, Rossetti M, Savineau JP, Ultman JS
Read more
January 1994 Revue des maladies respiratoires

[Mechanisms of bronchial hyperreactivity. Role of smooth muscle]

Authors : Marthan R, Stephens NL
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November 1993 European journal of pharmacology

Effect of vascular smooth muscle relaxants on the protein kinase C-mediated contraction in the rat pulmonary artery.

Authors : Savineau JP, Gonzalez De La Fuente P, Marthan R
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July 1993 Respiration physiology

Effect of in vitro exposure to acrolein on carbachol responses in rat trachealis muscle.

Authors : Ben-Jebria A, Marthan R, Rossetti M, Savineau JP, Ultman JS
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July 1993 The American review of respiratory disease

Sensitization decreases relaxation in human isolated airways.

Authors : Villanove X, Marthan R, Tunon de Lara JM, Johnson PR, Savineau JP, McKay KO, Alouan LA, Armour CL, Black JL
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May 1993 British journal of pharmacology

Effect of passive sensitization on the mechanical activity of human isolated bronchial smooth muscle induced by substance P, neurokinin A and VIP.

Authors : Ben-Jebria A, Marthan R, Rossetti M, Savineau JP
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March 1993 Pulmonary pharmacology

Effect of cromakalim on KCl-, noradrenaline- and angiotensin II-induced contractions in the rat pulmonary artery.

Authors : Savineau JP, Marthan R
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November 1992 Respiration physiology

Responsiveness to histamine in human sensitized airway smooth muscle.

Authors : Marthan R, Crevel H, Guénard H, Savineau JP
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August 1992 The American review of respiratory disease

Effect of in vitro nitrogen dioxide exposure on human bronchial smooth muscle response.

Authors : Ben-Jebria A, Marthan R, Savineau JP
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July 1992 Archives internationales de physiologie, de biochimie et de biophysique

[Cellular mechanism of muscle contraction of bronchial smooth muscle].

Authors : Marthan R
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May 1992 The Journal of allergy and clinical immunology

The effect of sodium cromoglycate on platelets: an in vivo and in vitro approach.

Authors : Tunon-de-Lara JM, Rio P, Marthan R, Vuillemin L, Ducassou D, Taytard A
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April 1992 Journal of neurology, neurosurgery, and psychiatry

Unilateral diaphragmatic paralysis: an electrophysiological study.

Authors : Lagueny A, Ellie E, Saintarailles J, Marthan R, Barat M, Julien J
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January 1992 Revue des maladies respiratoires

[A dyspnea of unusual cause in a chronic bronchitis patient]

Authors : Villanueva P, Tunon de Lara JM, Marthan R, Taytard A
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January 1992 Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

IgE binding inhibits arachidonic acid-induced chemiluminescence of human platelets.

Authors : Rio P, Tunon de Lara JM, Marthan R, Taytard A
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November 1991 British journal of pharmacology

Contraction of vascular smooth muscle induced by phorbol 12,13 dibutyrate in human and rat pulmonary arteries.

Authors : Savineau JP, Marthan R, Crevel H
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November 1989 The American review of respiratory disease

Is a myogenic response involved in deep inspiration-induced bronchoconstriction in asthmatics?

Authors : Marthan R, Woolcock AJ
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October 1989 The Journal of allergy and clinical immunology

Sensitization alters contractile responses and calcium influx in human airway smooth muscle.

Authors : Black JL, Marthan R, Armour CL, Johnson PR
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May 1989 Journal of applied physiology (Bethesda, Md. : 1985)

Solubility of Freon 22 in human blood and lung tissue.

Authors : Varene N, Choukroun ML, Marthan R, Varene P
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April 1989 Journal of applied physiology (Bethesda, Md. : 1985)

Calcium channel currents in isolated smooth muscle cells from human bronchus.

Authors : Marthan R, Martin C, Amédée T, Mironneau J
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January 1989 Revue des maladies respiratoires

[Calcium antagonists and chronic obstructive bronchopneumopathies]

Authors : Hilbert G, Marthan R, Vergeret J, Taytard A
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September 1988 Journal of autonomic pharmacology

Prostaglandin F2 alpha augments the response to parasympathetic fibre stimulation in an isolated innervated preparation of rabbit trachea.

Authors : Armour CL, Johnson PR, Marthan R, Black JL
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February 1988 Respiration physiology

Extracellular calcium and human isolated airway muscle: ionophore A23187 induced contraction.

Authors : Marthan R, Armour CL, Johnson PR, Black JL
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January 1988 Progress in clinical and biological research

Is airway hyperresponsiveness a smooth muscle abnormality?

Authors : Black J, Marthan R, Armour C, Johnson P
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February 1987 Respiration physiology

Acetylcholine-induced contraction in human isolated bronchial smooth muscle: role of an intracellular calcium store.

Authors : Marthan R, Savineau JP, Mironneau J
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January 1987 The American review of respiratory disease

The calcium channel agonist BAY K8644 enhances the responsiveness of human airway muscle to KCl and histamine but not to carbachol.

Authors : Marthan R, Armour CL, Johnson PR, Black JL
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April 1985 Chest

Gas exchange alterations in patients with chronic obstructive lung disease.

Authors : Marthan R, Castaing Y, Manier G, Guenard H
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January 1985 Revue des maladies respiratoires

[The inert gas method in respiratory physiopathology]

Authors : Guenard H, Manier G, Castaing Y, Marthan R
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April 1983 Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression

[A case of postoperative meningitis caused by 3 gram-negative bacteria]

Authors : Maurette P, Dabadie P, Stricker A, Marthan R, Chevais R
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