Members

Sabine CHARRON

Engineer

Email : [email protected]
ORCID : 0000-0002-7509-7666

Professional background

https://www.linkedin.com/in/sabine-charron-guitoger-70341997/

Depuis 2013 : IHU Liryc – Equipe 3 CRCTB – INSERM U1045 / Ingénieure d’Etudes
2012 : CHU de Bordeaux / Technicienne de Laboratoire
2009-2012 : Université de Bordeaux – CNRS UMR 5234 / Ingénieure d’Etudes
2006-2009 : Université d’Orléans – CNRS UMR 6218 / Ingénieure d’Etudes
2005 : Stage de Master Professionnel – LVMH Recherche (St Jean de Braye-45)
2004 : Stage de Maîtrise – Université de Poitiers – CNRS UMR 6008
2002 : Stage de DUT – INRA (Villenave d’Ornon-33)

Publications 21

February 2026 JACC. Clinical electrophysiology

Endocardial Ito-slow Overexpression and Fibrotic Remodeling Underlying Pause-Dependent Early Repolarization in Humans

Authors : Walton RD, Renard E, Haïssaguerre M, Benoist D, Chaigne S, Charron S, Cheniti G, Constantin M, Denis A, Douard M, Dubes V, Duchateau J, Guicheney P, Guillot B, Hof T, Magat J, Martinez ME, Michel C, Pallares-Lupon N, Vaillant F, Labrousse L, Nubret K, Rogier J, Vigmond EJ, Hocini M, Bernus O
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January 2023 Frontiers in Physiology

Inhibition of EPAC1 signaling pathway alters atrial electrophysiology and prevents atrial fibrillation

Authors : Guillot, B., Boileve, A., Walton, R., Harfoush, A., Conte, C., Sainte-Marie, Y., Charron, S., Bernus, O., Recalde, A., Sallé, L., Brette, F., Lezoualc’h, F.
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January 2023 Jacc Clinical Electrophysiology

Functional Epicardial Conduction Disturbances Due to a SCN5A Variant Associated With Brugada Syndrome

Authors : Renard, E., Walton, R.D., Benoist, D., Brette, F., Bru-Mercier, G., Chaigne, S., Charron, S., Constantin, M., Douard, M., Dubes, V., Guillot, B., Hof, T., Magat, J., Martinez, M.E., Michel, C., Pallares-Lupon, N., Pasdois, P., Récalde, A., Vaillant, F., Sacher, F., Labrousse, L., Rogier, J., Kyndt, F., Baudic, M., Schott, J.-J., Barc, J., Probst, V., Sarlandie, M., Marionneau, C., Ashton, J.L., Hocini, M., Haïssaguerre, M., Bernus, O.
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July 2022 Frontiers in physiology

Assessment of Cardiac Toxicity of Manganese Chloride for Cardiovascular Magnetic Resonance.

Authors : Lamonzie E, Vaillant F, Abell E, Charron S, El Hamrani D, Quesson B, Brette F
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January 2021 Magma (New York, N.Y.)

3D magnetization transfer (MT) for the visualization of cardiac free-running Purkinje fibers: an ex vivo proof of concept.

Authors : Magat J, Fouillet A, Constantin M, Haliot K, Naulin J, El Hamrani D, Benoist D, Charron S, Walton R, Bernus O, Quesson B
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January 2021 American journal of physiology. Heart and circulatory physiology

Transient receptor potential vanilloid 4 channel participates in mouse ventricular electrical activity.

Authors :
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October 2018 Circulation. Arrhythmia and electrophysiology

Arrhythmogenic Remodeling of the Left Ventricle in a Porcine Model of Repaired Tetralogy of Fallot.

Authors : Dubes V, Benoist D, Roubertie F, Gilbert SH, Constantin M, Charron S, Elbes D, Vieillot D, Quesson B, Cochet H, Haïssaguerre M, Rooryck C, Bordachar P, Thambo JB, Bernus O
Read more
March 2017 Clinical genetics

Deletion of the transcription factor SOX4 is implicated in syndromic nephroblastoma.

Authors : Trimouille A, Barouk-Simonet E, Charron S, Bouron J, Bernhard JC, Lacombe D, Fergelot P, Rooryck C
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October 2016 Heart (British Cardiac Society)

Proarrhythmic remodelling of the right ventricle in a porcine model of repaired tetralogy of Fallot.

Authors : Benoist D, Dubes V, Roubertie F, Gilbert SH, Charron S, Constantin M, Elbes D, Vieillot D, Quesson B, Cochet H, Haïssaguerre M, Rooryck C, Bordachar P, Thambo JB, Bernus O
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June 2016 Journal of medical genetics

Mutations in MYT1, encoding the myelin transcription factor 1, are a rare cause of OAVS.

Authors : Lopez E, Berenguer M, Tingaud-Sequeira A, Marlin S, Toutain A, Denoyelle F, Picard A, Charron S, Mathieu G, de Belvalet H, Arveiler B, Babin PJ, Lacombe D, Rooryck C
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August 2015 PloS one

Identification of Region-Specific Myocardial Gene Expression Patterns in a Chronic Swine Model of Repaired Tetralogy of Fallot.

Authors : Charron S, Roubertie F, Benoist D, Dubes V, Gilbert SH, Constantin M, Vieillot D, Elbes D, Quesson B, Bordachar P, Haissaguerre M, Bernus O, Thambo JB, Rooryck C
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January 2012 Journal of immunology (Baltimore, Md. : 1950)

IL-12Rβ2 is essential for the development of experimental cerebral malaria.

Authors : Fauconnier M, Palomo J, Bourigault ML, Meme S, Szeremeta F, Beloeil JC, Danneels A, Charron S, Rihet P, Ryffel B, Quesniaux VF
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August 2011 PloS one

IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis.

Authors : Gasse P, Riteau N, Vacher R, Michel ML, Fautrel A, di Padova F, Fick L, Charron S, Lagente V, Eberl G, Le Bert M, Quesniaux VF, Huaux F, Leite-de-Moraes M, Ryffel B, Couillin I
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February 2011 American journal of respiratory and critical care medicine

Dual Role of IL-22 in allergic airway inflammation and its cross-talk with IL-17A.

Authors : Besnard AG, Sabat R, Dumoutier L, Renauld JC, Willart M, Lambrecht B, Teixeira MM, Charron S, Fick L, Erard F, Warszawska K, Wolk K, Quesniaux V, Ryffel B, Togbe D
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December 2010 The American journal of pathology

Protein kinase C-theta is required for development of experimental cerebral malaria.

Authors : Fauconnier M, Bourigault ML, Meme S, Szeremeta F, Palomo J, Danneels A, Charron S, Fick L, Jacobs M, Beloeil JC, Ryffel B, Quesniaux VF
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August 2010 The Journal of infectious diseases

Interleukin 17 receptor signaling is deleterious during Toxoplasma gondii infection in susceptible BL6 mice.

Authors : Guiton R, Vasseur V, Charron S, Arias MT, Van Langendonck N, Buzoni-Gatel D, Ryffel B, Dimier-Poisson I
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December 2009 Journal of immunology (Baltimore, Md. : 1950)

IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema.

Authors : Couillin I, Vasseur V, Charron S, Gasse P, Tavernier M, Guillet J, Lagente V, Fick L, Jacobs M, Coelho FR, Moser R, Ryffel B
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June 2009 The Journal of biological chemistry

Mycobacterial phosphatidylinositol mannosides negatively regulate host Toll-like receptor 4, MyD88-dependent proinflammatory cytokines, and TRIF-dependent co-stimulatory molecule expression.

Authors : Doz E, Rose S, Court N, Front S, Vasseur V, Charron S, Gilleron M, Puzo G, Fremaux I, Delneste Y, Erard F, Ryffel B, Martin OR, Quesniaux VF
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February 2009 American journal of respiratory and critical care medicine

Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis.

Authors : Gasse P, Riteau N, Charron S, Girre S, Fick L, Pétrilli V, Tschopp J, Lagente V, Quesniaux VF, Ryffel B, Couillin I
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December 2007 The Journal of clinical investigation

IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice.

Authors : Gasse P, Mary C, Guenon I, Noulin N, Charron S, Schnyder-Candrian S, Schnyder B, Akira S, Quesniaux VF, Lagente V, Ryffel B, Couillin I
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May 2007 The American journal of pathology

Murine cerebral malaria development is independent of toll-like receptor signaling.

Authors : Togbe D, Schofield L, Grau GE, Schnyder B, Boissay V, Charron S, Rose S, Beutler B, Quesniaux VF, Ryffel B
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Team

Team 3

Cardiac electrophysiology

Specializing in the study and treatment of fibrillatory arrhythmias and dyssynchrony, this team has advanced expertise in rhythmology, experimental electrophysiology, signal processing, and clinical imaging.

Leadership : Olivier BERNUS