Members

Elise MAURAT

Engineer

Email : [email protected]
ORCID : 0000-0002-3489-6533

Professional background

Since 2012: Research Engineer in Cell Biology – CRCTB, INSERM U1045, University of Bordeaux

2008–2011: Research Technician – MRGM, INSERM U1211, University of Bordeaux
Identification of genetic mutations and investigation of their functional consequences in neurodegenerative diseases (ARSACS, periventricular nodular heterotopias)

2006–2007: R&D Technician – MDS Pharma Services, Lyon, France
Pharmacovigilance of therapeutic compounds

2005: R&D Technician – Servier, Orléans, France
Screening of therapeutic compounds

2004–2005: R&D Technician – CERB, Bourges, France
Pharmacovigilance of therapeutic compounds

Education
2025 – Institutional Diploma in Life and Earth Sciences – EPHE, PSL University
2017 – Bachelor’s Degree GBMQ – University of Nice
2004 – University Diploma of Technology (DUT) in Biological and Biochemical Analysis – University of Clermont Auvergne

Publications 24

January 2025 bioRxiv

Tunable 3D Alveolosphere Model from Human Alveolar Cells: A Breakthrough Tool to Explore Emphysema Pathophysiology

Authors :
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December 2024 European Respiratory Journal

A novelin vitrotubular model to recapitulate features of distal airways: the bronchioid

Authors : Elise Maurat, Katharina Raasch, Alexander M. Leipold, Pauline Henrot, Maeva Zysman, Renaud Prevel, Thomas Trian, Tobias Krammer, Vanessa Bergeron, Matthieu Thumerel, Pierre Nassoy, Patrick Berger, Antoine-Emmanuel Saliba, Laetitia Andrique, Gaëlle Recher, Isabelle Dupin
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January 2024 Respiratory Research

Pulmonary adaptation to repeated poly(I:C) exposure is impaired in asthmatic mice: an observational study

Authors : Allard, B., Ousova, O., Savitskaya, Z., Levardon, H., Maurat, E., Campagnac, M., Trian, T., Berger, P.
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January 2024 American Journal of Respiratory and Critical Care Medicine

Bronchial Remodeling Identifies New Endotypes in Severe Preschool Wheezers

Authors : Beaufils, F., Mondenx, M., Fayon, M., Menard, J., Begueret, H., Michelet, M., Berger, P., Bui, S., Campagnac, M., Esteves, P., Feghali, H., Galode, F., Labouret, G., Lavrand, F., Martin-Blondel, A., Marais, S., Maurat, E., Mittaine, M., Ousova, O., Rouquette, I., Siao-Him-Fa, V., Trian, T.
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January 2024 bioRxiv

A novel in vitro tubular model to recapitulate features of distal airways: The bronchioid

Authors :
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January 2023 Elife

Short-range interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammatory response

Authors : Eyraud, E., Maurat, E., Sac-Epée, J.-M., Henrot, P., Zysman, M., Esteves, P., Trian, T., Dupuy, J.-W., Leipold, A., Saliba, A.-E., Begueret, H., Girodet, P.-O., Thumerel, M., Hustache-Castaing, R., Marthan, R., Levet, F., Vallois, P., Contin-Bordes, C., Berger, P., Dupin, I.
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January 2023 Journal of Theoretical Biology

Probabilistic cellular automata modelling of intercellular interactions in airways: complex pattern formation in patients with chronic obstructive pulmonary disease

Authors : Dupin, I., Eyraud, E., Maurat, É., Sac-Épée, J.-M., Vallois, P.
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January 2023 bioRxiv

CXCR4 blockade alleviates pulmonary and cardiac outcomes in young COPD

Authors :
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January 2023 American Journal of Respiratory and Critical Care Medicine

Bronchial Remodeling-based Latent Class Analysis Predicts Exacerbations in Severe Preschool Wheezers

Authors : Fayon, M., Beaufils, F., Esteves, P., Campagnac, M., Maurat, E., Michelet, M., Siao-Him-Fa, V., Lavrand, F., Simon, G., Begueret, H., Berger, P.
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July 2022 Journal of Allergy and Clinical Immunology

Rhinovirus infection of bronchial epithelium induces specific bronchial smooth muscle cell migration of severe asthmatic patients

Authors : Alexis Celle, Pauline Esteves, Guillaume Cardouat, Fabien Beaufils, Edmée Eyraud, Isabelle Dupin, Elise Maurat, Sabrina Lacomme, Olga Ousova, Hugues Begueret, Matthieu Thumerel, Roger Marthan, Pierre-Olivier Girodet, Patrick Berger, Thomas Trian
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March 2022 Cell Reports

Asthmatic bronchial smooth muscle increases rhinovirus replication within the bronchial epithelium

Authors : Pauline Esteves, Benoit Allard, Alexis Celle, Isabelle Dupin, Elise Maurat, Olga Ousova, Matthieu Thumerel, Jean-William Dupuy, Thierry Leste-Lasserre, Roger Marthan, Pierre-Olivier Girodet, Thomas Trian, Patrick Berger
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January 2022 Frontiers in Pharmacology

Muscarinic receptor M3 activation promotes fibrocytes contraction

Authors : Henrot, P., Eyraud, E., Maurat, E., Point, S., Cardouat, G., Quignard, J.-F., Esteves, P., Trian, T., Girodet, P.-O., Marthan, R., Zysman, M., Berger, P., Dupin, I.
Read more
January 2022 bioRxiv

Short-range interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammatory response

Authors : Eyraud, E., Maurat, E., Sac-Epée, J.-M., Henrot, P., Zysman, M., Esteves, P., Trian, T., Bégueret, H., Girodet, P.-O., Thumerel, M., Hustache-Castaing, R., Marthan, R., Levet, F., Vallois, P., Contin-Bordes, C., Berger, P., Dupin, I.
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December 2021 European Respiratory Journal

Circulating fibrocytes as a new tool to predict lung cancer progression after surgery?

Authors : Pauline Henrot, Fabien Beaufils, Matthieu Thumerel, Edmée Eyraud, Augustin Boudoussier, Hugues Begueret, Elise Maurat, Pierre-Olivier Girodet, Roger Marthan, Patrick Berger, Isabelle Dupin, Maéva Zysman
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January 2021 European Respiratory Journal

Crucial role of fatty acid oxidation in asthmatic bronchial smooth muscle remodelling

Authors : Esteves, P., Blanc, L., Celle, A., Dupin, I., Maurat, E., Amoedo, N., Cardouat, G., Ousova, O., Gales, L., Bellvert, F., Begueret, H., Thumerel, M., Dupuy, J.-W., Desbenoit, N., Marthan, R., Girodet, P.-O., Rossignol, R., Berger, P., Trian, T.
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January 2020 European Respiratory Journal

Connexin-43 is a promising target for pulmonary hypertension due to hypoxaemic lung disease

Authors : Bouvard, C., Genet, N., Phan, C., Rode, B., Thuillet, R., Tu, L., Robillard, P., Campagnac, M., Soleti, R., de la Roque, E.D., Delcambre, F., Cronier, L., Parpaite, T., Maurat, E., Berger, P., Savineau, J.-P., Marthan, R., Guignabert, C., Freund-Michel, V., Guibert, C.
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January 2020 Frontiers in Immunology

Asthmatic Bronchial Smooth Muscle Increases CCL5-Dependent Monocyte Migration in Response to Rhinovirus-Infected Epithelium

Authors : Allard, B., Levardon, H., Esteves, P., Celle, A., Maurat, E., Thumerel, M., Girodet, P.O., Trian, T., Berger, P.
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January 2019 European Respiratory Journal

Fibrocyte accumulation in the airway walls of COPD patients

Authors : Dupin, I., Thumerel, M., Maurat, E., Coste, F., Eyraud, E., Begueret, H., Trian, T., Montaudon, M., Marthan, R., Girodet, P.-O., Berger, P.
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October 2018

Fibrocyte accumulation in bronchi: a cellular hallmark of COPD

Authors : Isabelle Dupin, Matthieu Thumerel, Elise Maurat, Florence Coste, Hugues Begueret, Thomas Trian, Michel Montaudon, Roger Marthan, Pierre-Olivier Girodet, Patrick Berger
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January 2016 Journal of Allergy and Clinical Immunology

Selective dysfunction of p53 for mitochondrial biogenesis induces cellular proliferation in bronchial smooth muscle from asthmatic patients

Authors : Trian, T., Allard, B., Ozier, A., Maurat, E., Dupin, I., Thumerel, M., Ousova, O., Gillibert-Duplantier, J., Le Morvan, V., Begueret, H., Girodet, P.-O., Marthan, R., Berger, P.
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January 2016 Journal of Allergy and Clinical Immunology

Blood fibrocytes are recruited during acute exacerbations of chronic obstructive pulmonary disease through a CXCR4-dependent pathway

Authors : Dupin, I., Allard, B., Ozier, A., Maurat, E., Ousova, O., Delbrel, E., Trian, T., Bui, H.-N., Dromer, C., Guisset, O., Blanchard, E., Hilbert, G., Vargas, F., Thumerel, M., Marthan, R., Girodet, P.-O., Berger, P.
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January 2015 Annals of Neurology

New practical definitions for the diagnosis of autosomal recessive spastic ataxia of Charlevoix-Saguenay

Authors : Pilliod, J., Moutton, S., Lavie, J., Maurat, E., Hubert, C., Bellance, N., Anheim, M., Forlani, S., Mochel, F., N'Guyen, K., Thauvin-Robinet, C., Verny, C., Milea, D., Lesca, G., Koenig, M., Rodriguez, D., Houcinat, N., Van-Gils, J., Durand, C.M., Guichet, A., Barth, M., Bonneau, D., Convers, P., Maillart, E., Guyant-Marechal, L., Hannequin, D., Fromager, G., Afenjar, A., Chantot-Bastaraud, S., Valence, S., Charles, P., Berquin, P., Rooryck, C., Bouron, J., Brice, A., Lacombe, D., Rossignol, R., Stevanin, G., Benard, G., Burglen, L., Durr, A., Goizet, C., Coupry, I.
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January 2014 Plos One

Protease activated receptor-2 expression and function in asthmatic bronchial smooth muscle

Authors : Allard, B., Bara, I., Gilbert, G., Carvalho, G., Trian, T., Ozier, A., Gillibert-Duplantier, J., Ousova, O., Maurat, E., Thumerel, M., Quignard, J.-F., Girodet, P.-O., Marthan, R., Berger, P.
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January 2012 European Journal of Medical Genetics

Atypical male and female presentations of FLNA-related periventricular nodular heterotopia

Authors : Fergelot, P., Coupry, I., Rooryck, C., Deforges, J., Maurat, E., Solé, G., Boute, O., Dieux-Coeslier, A., David, A., Marchal, C., Thambo, J.-B., Lacombe, D., Arveiler, B., Goizet, C.
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Team

Team 2

Bronchial remodeling

The study of the mechanisms and treatments of bronchial remodeling in asthma and chronic bronchitis is at the heart of this team's work. It has recognized expertise in epithelium-muscle interactions, functional imaging and clinical research.

Leadership : Patrick BERGER