Fanny VAILLANT

Research Engineer

Professional background

2017 – … Research Engineer, Inserm U1045 – CRCTB, IHU-LIRYC, University of Bordeaux, Bordeaux (France)
2012 – 2017 Postdoctoral research fellow, U1045 – CRCTB, IHU-LIRYC, University of Bordeaux, (France)
2010 – 2012 Postdoctoral research fellow, Intermediary metabolism, Montreal Heart Institute, University of Montreal (Canada)
2007 – 2010 PhD student, University Claude Bernard Lyon (France) and Montreal Heart Institute, University of Montreal (Canada)

Funding

2012 Post-doctoral fellow grant “Fonds de la Recherche en Santé du Québec”
2011 Young investigator award (1st prize) Journées européennes de la Société Française de Cardiologie
2007 – 2010 Allocation recherche ministère de l’Enseignement Supérieur et de la Recherche

Patents

WO2016034590A1 Focussed ultrasound cardiac stimulation system, portable device and cardiac stimulation, and associated methods. Fabrice MARQUET, Pierre Bour, Bruno Quesson, Fanny VAILLANT, Remi Dubois
WO 2016034594 A1 System for the ablation or the monitoring of a zone of the heart by ultrasounds and associated methods. Fabrice MARQUET, Pierre Bour, Bruno Quesson, Fanny VAILLANT

Publications 39

January 2026

Structural Characterization of Cardiac Purkinje Fibers Using Inhomogeneous Magnetization Transfer (ihMT): A proof of Concept MRI-Histology Approach

Authors : Arash Forodighasemabadi, Evgenios N. Kornaropoulos, Marion Constantin, Lucas Soustelle, Fanny Vaillant, Jude Leury, Richard Walton, Olivier Bernus, Bruno Quesson, Olivier M. Girard, Guillaume Duhamel, Julie Magat
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January 2025 Biorxiv

Resistance to Atrial Fibrillation Domestication and Mitochondrial Dysfunction in Sheep: a potential key role of the TCA Cycle and mitochondrial redox state

Authors : Caluori, G., Nattel, S., Pinson, B., Naud, P., Beauvoit, B., Claverol, S., Vaillant, F., Charron, S., Guilloteau, F., Loyer, V., Constantin, M., Popa, M., Belykh, A., Haeberlin, A., Ploux, S., Mahamat, H.A., Dubois, R., Guillot, B., Krisai, P., Kamakura, T., Bernus, O., Jaïs, P., Santos, P.D., Pasdois, P.
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January 2025 The Journal of Physiology

Influence of pericardium on ventricular mechanical interdependence in an isolated biventricular working pig heart model

Authors : Fanny Vaillant, Emma Abell, Laura R. Bear, Guido Caluori, Charly Belterman, Ruben Coronel, Sylvain Ploux, Pierre Dos Santos
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October 2023 Frontiers in cardiovascular medicine

Remotely detuned receiver coil for high-resolution interventional cardiac magnetic resonance imaging.

Authors : Marhabaie S, Delcey M, El Hamrani D, Vaillant F, Ginefri JC, Ozenne V, Abell E, Poirier-Quinot M, Quesson B
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January 2023 Journal of Cardiovascular Magnetic Resonance

Cardiac structure discontinuities revealed by ex-vivo microstructural characterization. A focus on the basal inferoseptal left ventricle region

Authors : Cabanis, P., Magat, J., Rodriguez-Padilla, J., Ramlugun, G., Yon, M., Bihan-Poudec, Y., Pallares-Lupon, N., Vaillant, F., Pasdois, P., Jais, P., Dos-Santos, P., Constantin, M., Benoist, D., Pourtau, L., Dubes, V., Rogier, J., Labrousse, L., Haissaguerre, M., Bernus, O., Quesson, B., Walton, R., Duchateau, J., Vigmond, E., Ozenne, V.
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January 2023 Jacc Clinical Electrophysiology

Functional Epicardial Conduction Disturbances Due to a SCN5A Variant Associated With Brugada Syndrome

Authors : Renard, E., Walton, R.D., Benoist, D., Brette, F., Bru-Mercier, G., Chaigne, S., Charron, S., Constantin, M., Douard, M., Dubes, V., Guillot, B., Hof, T., Magat, J., Martinez, M.E., Michel, C., Pallares-Lupon, N., Pasdois, P., Récalde, A., Vaillant, F., Sacher, F., Labrousse, L., Rogier, J., Kyndt, F., Baudic, M., Schott, J.-J., Barc, J., Probst, V., Sarlandie, M., Marionneau, C., Ashton, J.L., Hocini, M., Haïssaguerre, M., Bernus, O.
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January 2023 Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

Cardiac structure discontinuities revealed by ex-vivo microstructural characterization. A focus on the basal inferoseptal left ventricle region

Authors : Cabanis P, Magat J, Rodriguez-Padilla J, Ramlugun G, Yon M, Bihan-Poudec Y, Pallares-Lupon N, Vaillant F, Pasdois P, Jais P, Dos-Santos P, Ozenne V
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July 2022 Frontiers in physiology

Assessment of Cardiac Toxicity of Manganese Chloride for Cardiovascular Magnetic Resonance.

Authors : Lamonzie E, Vaillant F, Abell E, Charron S, El Hamrani D, Quesson B, Brette F
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March 2022 American journal of physiology. Heart and circulatory physiology

Impact of Intraventricular Septal Fiber Orientation on Cardiac Electromechanical Function.

Authors : Rodriguez Padilla J, Petras A, Magat J, Bayer J, Bihan-Poudec Y, El-Hamrani D, Ramlugun G, Neic A, Augustin C, Vaillant F, Constantin M, Benoist D, Vigmond E
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March 2022 IEEE transactions on ultrasonics, ferroelectrics, and frequency control

Spectral Analysis of Tissue Displacement for Cardiac Activation Mapping: Ex Vivo Working Heart and In Vivo Study.

Authors : Robert J, Bessiere F, Cao E, Loyer V, Abell E, Vaillant F, Quesson B, Catheline S, Lafon C
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August 2021 Heart Rhythm

B-011-04 ABLATION SCAR IN A SINGLE PULMONARY VEIN CAUSES PROARRHYTHMIC MECHANICAL DESTABILIZATION IN HEALTHY SHEEP ATRIA

Authors : Lisa Amalie Gottlieb, Fanny Vaillant, Emma Abell, Charly Belterman, Dounia El-Hamrani, Jerome Naulin, Jerome Lamy, Nadjia Kachenoura, Bruno Quesson, Ruben Coronel, Lukas Dekker
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August 2021 Frontiers in physiology

Localized Pulmonary Vein Scar Promotes Atrial Fibrillation in High Left Atrial Pressure.

Authors : Gottlieb LA, Vaillant F, Abell E, Belterman C, Loyer V, El Hamrani D, Naulin J, Constantin M, Quesson B, Boukens BJ, Coronel R, Dekker LRC
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January 2021 American journal of physiology. Heart and circulatory physiology

Transient receptor potential vanilloid 4 channel participates in mouse ventricular electrical activity.

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October 2020 Heart Rhythm

Critical repolarization gradients determine the induction of reentry-based torsades de pointes arrhythmia in models of long QT syndrome

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February 2020 Biophysical Journal

Hexosamine Pathway Induces Cardiac Arrhythmia via Modulation of Sustained Potassium Currentmodulation of Sustained Potassium Current

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November 2019 Ultrasound in medicine & biology

High Frame Rate Ultrasound for Electromechanical Wave Imaging to Differentiate Endocardial From Epicardial Myocardial Activation.

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March 2017 Respiratory research

Chronic hypoxia aggravates monocrotaline-induced pulmonary arterial hypertension: a rodent relevant model to the human severe form of the disease.

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March 2017 Journal of therapeutic ultrasound

International Society for Therapeutic Ultrasound Conference 2016: Tel Aviv, Israel. 14-18 March, 2016.

Authors : Fowlkes B, Ghanouni P, Sanghvi N, Coussios C, Lyon PC, Gray M, Mannaris C, Victor MdS, Stride E, Cleveland R, Carlisle R, Wu F, Middleton M, Davies C
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January 2017 Clinical Cardiac Pacing, Defibrillation and Resynchronization Therapy

Leadless Pacing

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November 2016 Scientific reports

Non-invasive cardiac pacing with image-guided focused ultrasound.

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August 2016 American journal of physiology. Heart and circulatory physiology

Ivabradine and metoprolol differentially affect cardiac glucose metabolism despite similar heart rate reduction in a mouse model of dyslipidemia.

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March 2016 American journal of physiology. Heart and circulatory physiology

Magnetic resonance-compatible model of isolated working heart from large animal for multimodal assessment of cardiac function, electrophysiology, and metabolism.

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August 2015 Methods in enzymology

Metabolic Tracing Using Stable Isotope-Labeled Substrates and Mass Spectrometry in the Perfused Mouse Heart.

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March 2015 IRBM

Magnetic Resonance Imaging guided cardiac radiofrequency ablation

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November 2013 American journal of physiology. Heart and circulatory physiology

Mouse strain differences in metabolic fluxes and function of ex vivo working hearts.

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December 2012 Naunyn-Schmiedeberg's archives of pharmacology

Trimetazidine demonstrated cardioprotective effects through mitochondrial pathway in a model of acute coronary ischemia.

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November 2012 Journal of molecular and cellular cardiology

Metabolic effects of glutamine on the heart: anaplerosis versus the hexosamine biosynthetic pathway.

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August 2012 Resuscitation

Ivabradine but not propranolol delays the time to onset of ischaemia-induced ventricular fibrillation by preserving myocardial metabolic energy status.

Authors : Vaillant F, Dehina L, Dizerens N, Bui-Xuan B, Tabib A, Lauzier B, Chevalier P, Descotes J, Timour Q
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June 2012 Journal of Trace Elements in Medicine and Biology

Involvement of neuroleptic drugs in selenium deficiency and sudden death of cardiac origin: Study and human post-mortem examination

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April 2011 Journal of molecular and cellular cardiology

Post-translational modifications, a key process in CD36 function: lessons from the spontaneously hypertensive rat heart.

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April 2011 Resuscitation

Heart rate reduction with ivabradine increases ischaemia-induced ventricular fibrillation threshold: role of myocyte structure and myocardial perfusion.

Authors : Vaillant F, Dehina L, Mazzadi A, Descotes J, Chevalier P, Tabib A, Bui-Xuan B, Riera C, Belhani D, Timour Q
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January 2011 American journal of physiology. Heart and circulatory physiology

Ivabradine reduces heart rate while preserving metabolic fluxes and energy status of healthy normoxic working hearts.

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October 2010

Impact fonctionnel et métabolique d’une réduction de la fréquence cardiaque induite par un inhibiteur du courant If, l’ivabradine : approche expérimentale chez le porc et la souris

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August 2009 Human & Experimental Toxicology

Protective role of selenium supplementation against cardiac lesions induced by the combination of levomepromazine and risperidone in the rabbit

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May 2009 Cardiovascular toxicology

Cardiac lesions induced by testosterone: protective effects of dexrazoxane and trimetazidine.

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December 2008 Journal of cardiovascular pharmacology

Ivabradine induces an increase in ventricular fibrillation threshold during acute myocardial ischemia: an experimental study.

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November 2008 Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie

Heart lesions associated with anabolic steroid abuse: comparison of post-mortem findings in athletes and norethandrolone-induced lesions in rabbits.

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March 2008 Journal of applied toxicology : JAT

Role of selenium in heart lesions produced by neuroleptics in the rabbit.

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December 2007 Cardiovascular drugs and therapy

Trimetazidine protective effect against ischemia-induced susceptibility to ventricular fibrillation in pigs.

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