Sébastien IMBERT

Associate Professor- Hospital Practioner

Professional background

2025–2026: Visiting Researcher, Sydney Infectious Diseases Institute, University of Sydney
Since 2021: MCU-PH in Parasitology–Mycology, Parasitology–Mycology Department, CRCTB INSERM U1045, Bordeaux University Hospital and University of Bordeaux
2019–2021: AHU then PHU in Parasitology–Mycology, Bordeaux University Hospital and University of Bordeaux
2018–2020: PhD in Complexity of Living Systems, CIMI-Paris, UPMC UMRS CR7, INSERM U1135, CNRS ERL 8255, Sorbonne University
2016–2019: AHU in Parasitology–Mycology, Pitié-Salpêtrière Hospital and Sorbonne University
2011–2016: Medical Biology residency, AP-HP and Paris-Sud University
2006–2011: First and second cycles of Pharmacy studies, University of Montpellier

Funding

2025 Laureate of the “International Mobility for Research Staff” program of the University of Bordeaux (€20k)
2025 Laureate of the “RICAI/SFM International Mobility Grant” awarded by ACAI (€35k)
2025 STS Department Collaborative Call for Projects: Co–Principal Investigator of the APTAFUN project (€5k)
2024 SFMM Research Call: Principal Investigator of the WAIT-IV project (€5k)
2024 ANR AAPG: Partner in the INF-HOLOBIONT project (Prof. L. Delhaes), scientific lead for the CRCTB (€238k / €838k)
2021 GIRCI SOHO APITHEM: Principal Investigator of the MyCADO project (€70k)

Publications 41

March 2024 Journal of Medical Mycology

Severe kerion Celsi caused by Trichophyton quinckeanum

Authors : M. Lefranc, S. Fourmond, A. Jabet, A-C Normand, D. Girard, I. Accoceberry, F. Gabriel, L. Delhaes, S. Imbert
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January 2024 Medical Mycology

Performance of Mucorales spp. qPCR in bronchoalveolar lavage fluid for the diagnosis of pulmonary mucormycosis

Authors : Brousse, X., Imbert, S., Issa, N., Forcade, E., Faure, M., Chambord, J., Ramaroson, H., Kaminski, H., Dumas, P.-Y., Blanchard, E.
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October 2023 Microbiology Spectrum

The gut microbiota composition is linked to subsequent occurrence of ventilator-associated pneumonia in critically ill patients

Authors : Arthur Orieux, Raphaël Enaud, Sébastien Imbert, Philippe Boyer, Erwan Begot, Adrian Camino, Alexandre Boyer, Patrick Berger, Didier Gruson, Laurence Delhaes, Renaud Prevel
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April 2023 Microorganisms

Improving the Detection of Epidemic Clones in Candida parapsilosis Outbreaks by Combining MALDI-TOF Mass Spectrometry and Deep Learning Approaches

Authors : Noshine Mohammad, Anne-Cécile Normand, Cécile Nabet, Alexandre Godmer, Jean-Yves Brossas, Marion Blaize, Christine Bonnal, Arnaud Fekkar, Sébastien Imbert, Xavier Tannier, Renaud Piarroux
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April 2023 Antimicrobial Agents and Chemotherapy

Multicentric Analysis of the Species Distribution and Antifungal Susceptibility of Clinical Isolates from Aspergillus Section Circumdati

Authors : S. Imbert, A. C. Normand, D. Costa, F. Gabriel, L. Lachaud, C. Schuttler, S. Cassaing, C. Mahinc, L. Hasseine, M. Demar, S. Brun, C. Bonnal, A. Moreno-Sabater, P. Becker, R. Piarroux, A. Fekkar
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April 2023 Microbiology Spectrum

Lung Mycobiota α-Diversity Is Linked to Severity in Critically Ill Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Authors : Raphaël Enaud, Pierre Sioniac, Sebastien Imbert, Pierre-Laurent Janvier, Adrian Camino, Hoang-Nam Bui, Odile Pillet, Arthur Orieux, Alexandre Boyer, Patrick Berger, Didier Gruson, Laurence Delhaes, Renaud Prevel
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January 2023 Journal of Clinical Microbiology

A Multiplex PCR and DNA-Sequencing Workflow on Serum for the Diagnosis and Species Identification for Invasive Aspergillosis and Mucormycosis

Authors : S. Imbert, L. Portejoie, E. Pfister, B. Tauzin, M. Revers, J. Uthurriague, M. Hernandez-Grande, M.-E Lafon, C. Jubert, N. Issa, P.-Y Dumas, L. Delhaes, Kimberly E. Hanson
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January 2023 Frontiers in Cellular and Infection Microbiology

The gut-lung axis in the CFTR modulator era

Authors : Lussac-Sorton, F., Charpentier, É., Imbert, S., Lefranc, M., Bui, S., Fayon, M., Berger, P., Enaud, R., Delhaes, L.
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January 2023 Antimicrobial Agents and Chemotherapy

Evaluation of Gradient Concentration Strips for Detection of Terbinafine Resistance in Trichophyton spp.

Authors : Bidaud, A.-L., Moreno-Sabater, A., Normand, A.-C., Cremer, G., Foulet, F., Brun, S., Ayachi, A., Imbert, S., Chowdhary, A., Dannaoui, E.
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January 2023 Microbiology Spectrum

Effects of Lumacaftor-Ivacaftor on Airway Microbiota-Mycobiota and Inflammation in Patients with Cystic Fibrosis Appear To Be Linked to Pseudomonas aeruginosa Chronic Colonization

Authors : Enaud, R., Lussac-Sorton, F., Charpentier, E., Velo-Suárez, L., Guiraud, J., Bui, S., Fayon, M., Schaeverbeke, T., Nikolski, M., Burgel, P.-R., Héry-Arnaud, G., Delhaes, L., Imbert, S., Beaufils, F., Berger, P., Bébéar, C., Macey, J., Perry, F., Gallet, P., Simon, G., Guichoux, E., Massot, M., Tyssandier, B., Cornet, M., Pin, I., Llerena, C., Gouriou, S., Gerardin, M., Mariani, P., Ramel, S., Grenet, D., Cardot-Martin, E., Dubus, J.-C., Stremler-Le Bel, N., Baravalle-Einaud, M., Ranque, S., Mas, E., Mittaine, M., Cassaing, S., Wizla, N., Thumerelle, C., Turck, D., Loridant, S., Deleplanque, A.-S.
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January 2023 Medical Mycology

Reliability of a terbinafine agar containing method for the screening of dermatophyte resistance

Authors : Bidaud, A.-L., Normand, A.-C., Jabet, A., Brun, S., Delliere, S., Cremer, G., Foulet, F., Ayachi, A., Imbert, S., Hennequin, C., Dannaoui, É., Moreno-Sabater, A.
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October 2022 Journal of Fungi

MALDI-TOF Mass Spectrometry Online Identification of Trichophyton indotineae Using the MSI-2 Application

Authors : Anne-Cécile Normand, Alicia Moreno-Sabater, Arnaud Jabet, Samia Hamane, Geneviève Cremer, Françoise Foulet, Marion Blaize, Sarah Dellière, Christine Bonnal, Sébastien Imbert, Sophie Brun, Ann Packeu, Stéphane Bretagne, Renaud Piarroux
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March 2022 Frontiers in Medicine

Central Nervous System Cryptococcosis in Patients With Sarcoidosis: Comparison With Non-sarcoidosis Patients and Review of Potential Pathophysiological Mechanisms

Authors : Renaud Prevel, Vivien Guillotin, Sébastien Imbert, Patrick Blanco, Laurence Delhaes, Pierre Duffau
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January 2022 Research Square

Deep learning model coupled with proteomics to detect yeast epidemic clones across multiple hospitals

Authors : Mohammad, N., Normand, A.C., Nabet, C., Brossas, J.-Y., Blaize, M., Bonnal, C., Fekkar, A., Imbert, S., Piarroux, R., Tannier, X.
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January 2022 Medical Mycology

Detection of circulating DNA for the diagnosis of invasive fusariosis: retrospective analysis of 15 proven cases

Authors : Dellière, S., Guitard, J., Sabou, M., Angebault, C., Moniot, M., Cornu, M., Hamane, S., Bougnoux, M.-E., Imbert, S., Pasquier, G., Botterel, F., Garcia-Hermoso, D., Alanio, A.
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January 2022 Emerging Infectious Diseases

Extensive Dermatophytosis Caused by Terbinafi ne-Resistant Trichophyton indotineae, France

Authors : Jabet, A., Brun, S., Normand, A.-C., Imbert, S., Akhoundi, M., Dannaoui, E., Audiffred, L., Chasset, F., Izri, A., Laroche, L., Piarroux, R., Bachmeyer, C., Hennequin, C., Sabater, A.M.
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November 2021 Mycoses

Invasive aspergillosis due to Aspergillus cryptic species: A prospective multicentre study

Authors : Sebastien Imbert, Sophie Cassaing, Christine Bonnal, Anne‐Cecile Normand, Frederic Gabriel, Damien Costa, Marion Blaize, Laurence Lachaud, Lilia Hasseine, Lise Kristensen, Juliette Guitard, Christine Schuttler, Helene Raberin, Sophie Brun, Marijke Hendrickx, Renaud Piarroux, Arnaud Fekkar
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January 2021 Journal of Fungi

Clinical origin and species distribution of fusarium spp. Isolates identified by molecular sequencing and mass spectrometry: A european multicenter hospital prospective study

Authors : Normand, A.-C., Imbert, S., Brun, S., Al-Hatmi, A.M.S., Chryssanthou, E., Cassaing, S., Schuttler, C., Hasseine, L., Mahinc, C., Costa, D., Bonnal, C., Ranque, S., Sautour, M., Rubio, E., Delhaes, L., Riat, A., Sendid, B., Kristensen, L., Brandenberger, M., Guitard, J., Packeu, A., Piarroux, R., Fekkar, A.
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January 2021 Journal of Clinical Microbiology

Identification of Molds with Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry: Performance of the Newly Developed MSI-2 Application in Comparison with the Bruker Filamentous Fungi Database and MSI-1

Authors : Normand, A.-C., Blaize, M., Imbert, S., Packeu, A., Becker, P., Fekkar, A., Stubbe, D., Piarrouxa, R.
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January 2021 Open Forum Infectious Diseases

Poppers, by Inducing HHV-8 Virion Production, Can Act as a Promoter for HHV-8 Transmission in Men Who Have Sex with Men

Authors : Jary, A., Gothland, A., Palich, R., Leducq, V., Monsel, G., Imbert, S., Schneider, L., Simon, A., Spano, J.-P., Katlama, C., Larabi, I.A., Alvarez, J.-C., Calvez, V., Marcelin, A.-G.
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January 2021 Antimicrobial Agents and Chemotherapy

Antifungal susceptibility of 182 fusarium species isolates from 20 european centers: Comparison between eucast and gradient concentration strip methods

Authors : Blaize, M., Normand, A.-C., Imbert, S., Al-Hatmi, A.M.S., Chryssanthou, E., Cassaing, S., Schuttler, C., Hasseine, L., Mahinc, C., Costa, D., Bonnal, C., Ranque, S., Sautour, M., Rubio, E., Delhaes, L., Riat, A., Sendid, B., Kristensen, L., Brandenberger, M., Stubbe, D., Brun, S., Piarroux, R., Fekkar, A.
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January 2021 Antimicrobial Agents and Chemotherapy

Hospital outbreak of fluconazole-resistant candida parapsilosis: Arguments for clonal transmission and long-term persistence

Authors : Fekkar, A., Blaize, M., Bouglé, A., Normand, A.-C., Raoelina, A., Kornblum, D., Kamus, L., Piarroux, R., Imbert, S.
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January 2021 Journal of Molecular Diagnostics

Evaluation of a New Histoplasma spp. Quantitative RT-PCR Assay

Authors : Alanio, A., Gits-Muselli, M., Lanternier, F., Sturny-Leclère, A., Benazra, M., Hamane, S., Rodrigues, A.M., Garcia-Hermoso, D., Lortholary, O., Dromer, F., Bretagne, S., Woimant, M.G., blanchard, G., Silhadi, S., Vignier, N., Pitsch, A., Jidar, K., Traversier, N., Poisson, D., Lecointre, C., Foulet, F., Botterel, F., Ammar, N.A., Amsellem, Gabriel, F., Poirier, P., Cornu, M., Loridant, S., Morio, F., Boutoille, D., Jeddi, F., Hasseine, L., Ouissa, R., Toubas, D., Bailly, E., Désoubeaux, G., Ronez, E., Foulon, G., Lefrançois, S., Bonnal, C., Paugam, A., Dougados, M., Desroches, M., Barazzutti, H., Paleiron, N., rabodonirina, M., Catherinot, E., Cardot-Martin, E., Hiesse, C., Salvator, H., Aguilar, C., Gigandon, A., de Montpreville, T., Bougnoux, M.-E., Sitterlé, E., Fekkar, A., Imbert, S., Bleibtreu, A., Senghor, Y., Denis, B., Molina, J.-M., Liegeon, G., Munnier, A.-L., Malphettes, M., Denis, J., Berlioz-Arthaud, A., Lange, F., Chiaruzzi, M., Epelboin, L.
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October 2020 Medical Mycology

Unexpected mould diversity in clinical isolates from French Guiana and associated identification difficulties

Authors :
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September 2020 Antimicrobial Agents and Chemotherapy

Multicentric analysis of the species distribution and antifungal susceptibility of cryptic isolates from Aspergillus section Fumigati

Authors :
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January 2020 Antimicrobial Agents and Chemotherapy

Species distribution and comparison between eucast and gradient concentration strips methods for antifungal susceptibility testing of 112 aspergillus section nigri isolates

Authors : Carrara, B., Richards, R., Imbert, S., Morio, F., Sasso, M., Zahr, N., Normand, A.C., Le Pape, P., Lachaud, L., Ranque, S., Maubon, D., Piarroux, R., Fekkar, A.
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November 2019 Medical Mycology

Multi-centric evaluation of the online MSI platform for the identification of cryptic and rare species of Aspergillus by MALDI-TOF

Authors : Sébastien Imbert, Anne Cécile Normand, Frédéric Gabriel, Sophie Cassaing, Christine Bonnal, Damien Costa, Laurence Lachaud, Lilia Hasseine, Lise Kristensen, Christine Schuttler, Hélène Raberin, Sophie Brun, Marijke Hendrickx, Dirk Stubbe, Renaud Piarroux, Arnaud Fekkar
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January 2019 La Revue du praticien

Serological monitoring and prevention of toxoplasmosis during pregnancy,Surveillance sérologique et prévention de la toxoplasmose chez la femme enceinte

Authors : Paris, L., Imbert, S.
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November 2018 European Journal of Clinical Microbiology & Infectious Diseases

Interpretation of very low avidity indices acquired with the Liaison XL Toxo IgG avidity assay in dating toxoplasmosis infection

Authors : Frédérique Boquel, Lorra Monpierre, Sébastien Imbert, Feriel Touafek, Régis Courtin, Renaud Piarroux, Luc Paris
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October 2018 AIDS (London, England)

Distinct paradoxical inflammatory reaction followed by postantiretroviral therapy immune reconstitution syndrome in cryptococcal meningitis.

Authors : Gaillet A, Calin R, Imbert S, Ollivier M, Guillot H, Fekkar A, Pourcher V
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August 2018 Frontiers in Microbiology

Aspergillus PCR in Bronchoalveolar Lavage Fluid for the Diagnosis and Prognosis of Aspergillosis in Patients With Hematological and Non-hematological Conditions.

Authors : Imbert S, Meyer I, Palous M, Brossas JY, Uzunov M, Touafek F, Gay F, Trosini-Desert V, Fekkar A
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May 2018 Antimicrobial Agents and Chemotherapy

Species Identification and In Vitro Antifungal Susceptibility of Aspergillus terreus Species Complex Clinical Isolates from a French Multicenter Study

Authors : S. Imbert, A. C. Normand, S. Ranque, J. M. Costa, J. Guitard, I. Accoceberry, C. Bonnal, A. Fekkar, N. Bourgeois, S. Houzé, C. Hennequin, R. Piarroux, E. Dannaoui, F. Botterel
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January 2018 BMC Infectious Diseases

Aspergillus pseudodeflectus: a new human pathogen in liver transplant patients

Authors : Nawel Aït-Ammar, Eric Levesque, Jean-Benjamin Murat, Sébastien Imbert, Françoise Foulet, Eric Dannaoui, Françoise Botterel
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November 2017 Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Performance of Aspergillus PCR in cerebrospinal fluid for the diagnosis of cerebral aspergillosis.

Authors : Imbert S, Brossas JY, Palous M, Joly I, Meyer I, Fekkar A
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May 2017 European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

Interpretation of the Elecsys Toxo IgG avidity results for very low and very high index: study on 741 sera with a determined date of toxoplasmosis.

Authors : Fricker-Hidalgo H, L'Ollivier C, Bosson C, Imbert S, Bailly S, Dard C, Piarroux R, Paris L, Pelloux H
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October 2016 Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Discontinuation of echinocandin and azole treatments led to the disappearance of an FKS alteration but not azole resistance during clonal Candida glabrata persistent candidaemia.

Authors : Imbert S, Castain L, Pons A, Jacob S, Meyer I, Palous M, Vezinet C, Langeron O, Hennequin C, Monsel A, Fekkar A
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September 2016 The Journal of allergy and clinical immunology

Calcineurin inhibitors impair neutrophil activity against Aspergillus fumigatus in allogeneic hematopoietic stem cell transplant recipients.

Authors : Imbert S, Bresler P, Boissonnas A, Gauthier L, Souchet L, Uzunov M, Leblond V, Mazier D, Nguyen S, Fekkar A
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June 2016 Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Aspergillus PCR in serum for the diagnosis, follow-up and prognosis of invasive aspergillosis in neutropenic and nonneutropenic patients.

Authors : Imbert S, Gauthier L, Joly I, Brossas JY, Uzunov M, Touafek F, Brun S, Mazier D, Datry A, Gay F, Fekkar A
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January 2015 Parasite (Paris, France)

The impact of lowering the cut-off value on the sensitivity of the Platelia Elisa IgG (Bio-Rad) test for toxoplasmosis diagnosis.

Authors : Mouri O, Kendjo E, Touafek F, Fekkar A, Konte O, Imbert S, Courtin R, Mazier D, Paris L
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November 2014 Antimicrobial agents and chemotherapy

In vitro combination of voriconazole and miltefosine against clinically relevant molds.

Authors : Imbert S, Palous M, Meyer I, Dannaoui E, Mazier D, Datry A, Fekkar A
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September 2014 European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

Emergence of echinocandin-resistant Candida spp. in a hospital setting: a consequence of 10 years of increasing use of antifungal therapy?

Authors : Fekkar A, Dannaoui E, Meyer I, Imbert S, Brossas JY, Uzunov M, Mellon G, Nguyen S, Guiller E, Caumes E, Leblond V, Mazier D, Fievet MH, Datry A
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