décembre 2024
Programming the elongation of mammalian cell aggregates with synthetic gene circuits
Auteurs : Josquin Courte, Christian Chung, Naisargee Jain, Catcher Salazar, Neo Phuchane, Steffen Grosser, Calvin Lam, Leonardo Morsut
novembre 2024
Nature Communications
Control of spatio-temporal patterning via cell growth in a multicellular synthetic gene circuit
Auteurs : Marco Santorelli, Pranav S. Bhamidipati, Josquin Courte, Benjamin Swedlund, Naisargee Jain, Kyle Poon, Dominik Schildknecht, Andriu Kavanagh, Victoria A. MacKrell, Trusha Sondkar, Mattias Malaguti, Giorgia Quadrato, Sally Lowell, Matt Thomson, Leonardo Morsut
octobre 2023
Cellular and Molecular Life Sciences
Synapses do not facilitate prion-like transfer of alpha-synuclein: a quantitative study in reconstructed unidirectional neural networks
Auteurs : Josquin Courte, Ngoc Anh Le, Teng Pan, Luc Bousset, Ronald Melki, Catherine Villard, Jean-Michel Peyrin
janvier 2023
Methods in Molecular Biology
Propagation of Distinct α-Synuclein Strains Within Human Reconstructed Neuronal Network and Associated Neuronal Dysfunctions
Auteurs : Simona Gribaudo, Luc Bousset, Josquin Courte, Ronald Melki, Jean-Michel Peyrin, Anselme L. Perrier
avril 2022
ACS Synthetic Biology
Parameterized Computational Framework for the Description and Design of Genetic Circuits of Morphogenesis Based on Contact-Dependent Signaling and Changes in Cell–Cell Adhesion
Auteurs : Calvin Lam, Sajeev Saluja, George Courcoubetis, Dottie Yu, Christian Chung, Josquin Courte, Leonardo Morsut
octobre 2021
Quantitative study of alpha-synuclein prion-like spreading in fully oriented reconstructed neural networks reveals non-synaptic dissemination of seeding aggregates
Auteurs : Josquin Courte, Ngoc Anh Le, Luc Bousset, Ronald Melki, Catherine Villard, Jean-Michel Peyrin
décembre 2020
Scientific Reports
The expression level of alpha-synuclein in different neuronal populations is the primary determinant of its prion-like seeding
Auteurs :
juillet 2018
Cellular and Molecular Life Sciences
Cellular mechanisms responsible for cell-to-cell spreading of prions
Auteurs :
janvier 2018
Neurotoxicity Research
Neurotoxicity of the Cyanotoxin BMAA Through Axonal Degeneration and Intercellular Spreading
Auteurs :
janvier 2018
Methods in Cell Biology
Reconstruction of directed neuronal networks in a microfluidic device with asymmetric microchannels
Auteurs :